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N,N'-ethylenebis(iodoacetamide)

Known as: ethylenediamine bis(iodoacetamide) 
National Institutes of Health

Papers overview

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2019
2019
Clinical microtubule-targeting drugs are functionally divided into microtubule-destabilizing and microtubule-stabilizing agents… 
2010
2010
Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous… 
1987
1987
Microtubule assembly in vitro is sensitive to a variety of non-physiological sulfhydryl-oxidizing agents, but the physiological… 
1985
1985
1985
1985
We have developed a simple probe for certain functionally significant features of the tubulin molecule. When bovine brain tubulin… 
Highly Cited
1984
Highly Cited
1984
When bovine brain tubulin purified in the absence of GTP and MgCl2 is reacted with N,N'-ethylene-bis(iodoacetamide) (EBI), a… 
Highly Cited
1981
Highly Cited
1981
The sulfhydryl groups of tubulin are reported to play a role in regulating microtubule assembly and colchicine binding to tubulin… 
Highly Cited
1981
Highly Cited
1981
The antimitotic drugs colchicine, podophyllotoxin, and vinblastine are known to be potent inhibitors of microtubule…