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N,N'-ethylenebis(iodoacetamide)

Known as: ethylenediamine bis(iodoacetamide) 
 
National Institutes of Health

Papers overview

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2019
2019
Clinical microtubule-targeting drugs are functionally divided into microtubule-destabilizing and microtubule-stabilizing agents… Expand
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2018
2018
Graphical abstract Figure. No caption available. HighlightsNovel SAR‐information of the anti‐cancer agent 2‐methoxyestradiol is… Expand
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2010
2010
Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous… Expand
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1992
1992
Dolastatin 10 is an unusual peptide of marine origin which binds to tubulin in the vinblastine/maytansine/phomopsin-binding… Expand
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1987
1987
Microtubule assembly in vitro is sensitive to a variety of non-physiological sulfhydryl-oxidizing agents, but the physiological… Expand
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1985
1985
The synthetic anti-tumor drug 3-(1-anilinoethylidene)-5-benzylpyrrolidine-2,4-dione (TN-16) is known to block microtubule… Expand
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1985
1985
We have developed a simple probe for certain functionally significant features of the tubulin molecule. When bovine brain tubulin… Expand
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1984
1984
When bovine brain tubulin purified in the absence of GTP and MgCl2 is reacted with N,N'-ethylene-bis(iodoacetamide) (EBI), a… Expand
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1981
1981
The sulfhydryl groups of tubulin are reported to play a role in regulating microtubule assembly and colchicine binding to tubulin… Expand
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1981
1981
The antimitotic drugs colchicine, podophyllotoxin, and vinblastine are known to be potent inhibitors of microtubule… Expand
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