N,N'-ethylenebis(iodoacetamide)

Known as: ethylenediamine bis(iodoacetamide) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2016
01219812016

Papers overview

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2014
2014
Vascular disrupting agents (VDAs) constitute an innovative anticancer therapy that targets the tumor endothelium, leading to… (More)
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2010
2010
Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous… (More)
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1992
1992
Dolastatin 10 is an unusual peptide of marine origin which binds to tubulin in the vinblastine/maytansine/phomopsin-binding… (More)
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1987
1987
Microtubule assembly in vitro is sensitive to a variety of non-physiological sulfhydryl-oxidizing agents, but the physiological… (More)
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1987
1987
2-(4-Methyl-1-piperazinylmethyl) acrylophenone dihydrochloride (MPMAP) is a novel inhibitor of microtubule assembly in vitro and… (More)
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1985
1985
We have previously found (Ludueña, R. F., and Roach, M. C. (1981b) Biochemistry 20, 4444-4450) that colchicine and… (More)
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1985
1985
We have developed a simple probe for certain functionally significant features of the tubulin molecule. When bovine brain tubulin… (More)
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1984
1984
When bovine brain tubulin purified in the absence of GTP and MgCl2 is reacted with N,N'-ethylene-bis(iodoacetamide) (EBI), a… (More)
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1982
1982
Microtubule assembly is inhibited by anti-mitotic drugs such as colchicine or podophyllotoxin and also by sulfhydryl-oxidizing… (More)
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1981
1981
The sulfhydryl groups of tubulin are reported to play a role in regulating microtubule assembly and colchicine binding to tubulin… (More)
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