N(6)-carboxymethyllysine

Known as: carboxymethyl-lysine, N(epsilon)-(carboxymethyl)lysine, N(Epsilon)-Carboxymethyl-L-Lysine 
A lysine derivative found in proteins where the epsilon nitrogen of the amino acid residue is modified by a carboxymethyl group. This advanced… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Individuals with type 2 diabetes have a myriad of metabolic aberrations including increased inflammation, increasing… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Activation of the receptor for advanced glycation end products (RAGE) in diabetic vasculature is considered to be a key… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Oxidative stress (OS) and inflammatory mediators increase with aging. The levels of advanced glycation endproducts… (More)
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Highly Cited
2004
Highly Cited
2004
The accumulation of AGE is thought to play a role in the pathogenesis of chronic complications of diabetes mellitus and renal… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Advanced glycoxidation end products (AGEs), the derivatives of glucose-protein or glucose-lipid interactions, are… (More)
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Highly Cited
1999
Highly Cited
1999
Recent studies suggested that interruption of the interaction of advanced glycation end products (AGEs), with the signal… (More)
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Highly Cited
1997
Highly Cited
1997
N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to… (More)
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Highly Cited
1996
Highly Cited
1996
Nepsilon-(Carboxymethyl)lysine (CML) is an advanced glycation end product formed on protein by combined nonenzymatic glycation… (More)
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Highly Cited
1992
Highly Cited
1992
To investigate the contribution of glycation and oxidation reactions to the modification of insoluble collagen in aging and… (More)
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Highly Cited
1986
Highly Cited
1986
The chemistry of Maillard or browning reactions of glycated proteins was studied using the model compound, N alpha-formyl-N… (More)
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