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Blebbistatin is a recently discovered small molecule inhibitor showing high affinity and selectivity toward myosin II. Here we… Expand Contractile myocytes provide a test of the hypothesis that cells sense their mechanical as well as molecular microenvironment… Expand Cell migration involves dynamic and spatially regulated changes to the cytoskeleton and cell adhesion. The Rho GTPases play key… Expand Ca(2+) regulation of contraction in vertebrate striated muscle is exerted primarily through effects on the thin filament, which… Expand The small GTPase Rho is implicated in physiological functions associated with actin-myosin filaments such as cytokinesis, cell… Expand VISUALIZATION of single actin filaments by fluorescence microscopy1 led to the development of new in vitro assays for analysing… Expand A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results… Expand Muscle contraction consists of a cyclical interaction between myosin and actin driven by the concomitant hydrolysis of adenosine… Expand demomistnatiomi of ademiosi mie tn phosphatase ac tivity, two types of striated muscle fibers (Padykula amid Herman. J. Histochem… Expand Myosin was isolated from 14 different muscles (mammals, lower vertebrates, and invertebrates) of known maximal speed of… Expand