Myeloproliferation

Myeloproliferation involves both medullary and extramedullary proliferation of bone marrow constituents, such as erythroblasts, granulocytes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Excessive or inappropriate activation of the immune system can be deleterious to the organism, warranting multiple molecular… (More)
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Highly Cited
2011
Highly Cited
2011
The JAK2V617F constitutively activated tyrosine kinase is found in most patients with myeloproliferative neoplasms. While… (More)
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Highly Cited
2011
Highly Cited
2011
Somatic loss-of-function mutations in the ten-eleven translocation 2 (TET2) gene occur in a significant proportion of patients… (More)
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Highly Cited
2011
Highly Cited
2011
The role of autophagy, a lysosomal degradation pathway which prevents cellular damage, in the maintenance of adult mouse… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNA miR-146a has been implicated as a negative feedback regulator of NF-κB activation. Knockout of the miR-146a gene in… (More)
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2010
2010
Although NPM1 gene mutations leading to aberrant cytoplasmic expression of nucleophosmin (NPMc(+)) are the most frequent genetic… (More)
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Highly Cited
2007
Highly Cited
2007
Hematopoiesis is maintained by stem cells (HSCs) that undergo fate decisions by integrating intrinsic and extrinsic signals, with… (More)
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2007
2007
An interstitial deletion on chromosome 4q12 resulting in the formation of the FIP1L1-PDGFRA fusion protein is involved in the… (More)
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Highly Cited
1999
Highly Cited
1999
The MLL gene from human chromosome 11q23 is involved in >30 different chromosomal translocations resulting in a plethora of… (More)
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Highly Cited
1991
Highly Cited
1991
Juvenile chronic myelogenous leukemia (JCML) is a good model for the study of myeloproliferation because JCML hematopoietic… (More)
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