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Myeloid Leukemia, Chronic

Known as: Chronic Myeloid Leukemias, CML - Chronic Myelogenous Leukemia, CML 
A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Advances in chronic myeloid leukemia treatment, particularly regarding tyrosine kinase inhibitors, mandate regular updating of… 
Highly Cited
2013
Highly Cited
2013
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths expected in the United States in the… 
Highly Cited
2012
Highly Cited
2012
BackgroundThe Avogadro project has developed an advanced molecule editor and visualizer designed for cross-platform use in… 
Highly Cited
2010
Highly Cited
2010
BACKGROUND Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND The cause of chronic myeloid leukemia (CML) is a constitutively active BCR-ABL tyrosine kinase. Imatinib inhibits this… 
Highly Cited
2003
Highly Cited
2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… 
Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine… 
Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is… 
Review
2000
Review
2000
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph… 
Review
1999
Review
1999
Chronic myeloid leukemia (CML) is a clonal myeloproliferative expansion of transformed, primitive hematopoietic progenitor cells…