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Myeloid Cell Leukemia Sequence 1 Protein

Known as: Myeloid Cell Leukemia Sequence 1, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, Myeloid Cell Factor-1 
A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein… Expand
National Institutes of Health

Papers overview

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2014
2014
Mcl-1 is a member of the Bcl-2 family protein; its degradation is required for the initiation of apoptosis. The mechanism… Expand
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2011
2011
Die p53-Familie, besteht aus den transkriptionell aktiven (TA-) Isoformen p53, TAp63 und TAp73, die Apoptose induzieren, und… Expand
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2009
2009
ABSTRACT The hepatitis C virus (HCV) core protein is known to modulate apoptosis and contribute to viral replication and… Expand
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Highly Cited
2008
Highly Cited
2008
Activation of the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is a frequent occurrence in human cancers and a… Expand
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2006
2006
(Figure 1c). The lower rates of relapse in allogeneic transplantation compared with autologous bone marrow transplantation, the… Expand
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Highly Cited
2005
Highly Cited
2005
Increased levels of Mcl-1 (myeloid cell factor-1) have been reported in several cancers, suggesting an important role played by… Expand
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2005
2005
We recently identified spontaneous T-cell responses against Bcl2-derived peptides in patients suffering from cancers of different… Expand
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Highly Cited
2004
Highly Cited
2004
Interleukin 6 (IL-6) is a growth and survival factor for multiple myeloma cells. As we report here, the IL-6-dependent human… Expand
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Highly Cited
2002
Highly Cited
2002
Multiple myeloma (MM) is characterized by the accumulation of malignant plasma cells in the bone marrow caused primarily by… Expand
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2002
2002
Multiple myeloma (MM) is a B-cell malignancy characterized by the accumulation of malignant plasma cells with slow proliferative… Expand
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