Myelin Basic Proteins

Known as: MBP, Myelin Basic Protein [Chemical/Ingredient], basic myelin protein 
An abundant cytosolic protein that plays a critical role in the structure of multilamellar myelin. Myelin basic protein binds to the cytosolic sides… (More)

Topic mentions per year

Topic mentions per year

1971-2017
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Papers overview

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Highly Cited
2000
Highly Cited
2000
Partial injury to the spinal cord can propagate itself, sometimes leading to paralysis attributable to degeneration of initially… (More)
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Highly Cited
1999
Highly Cited
1999
In experimental animal models of multiple sclerosis demyelinating antibody responses are directed against the myelin… (More)
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Highly Cited
1997
Highly Cited
1997
Myelin basic protein (MBP) mRNA is localized to myelin produced by oligodendrocytes of the central nervous system. MBP mRNA… (More)
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Highly Cited
1995
Highly Cited
1995
Structural similarity between viral T cell epitopes and self-peptides could lead to the induction of an autoaggressive T cell… (More)
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Highly Cited
1995
Highly Cited
1995
Ramified microglia in the adult central nervous system (CNS) are the principal glial element up-regulating MHC class I and II… (More)
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Highly Cited
1994
Highly Cited
1994
We have generated TCR transgenic mice (T/R+) specific for myelin basic protein (MBP) and crossed them to RAG-1-deficient mice to… (More)
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Highly Cited
1994
Highly Cited
1994
Equal numbers of CD4+ T cells recognizing myelin basic protein (MBP) and proteolipid protein (PLP) are found in the circulation… (More)
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Highly Cited
1993
Highly Cited
1993
We constructed a transgenic mouse model that mimics the human autoimmune disease multiple sclerosis in its spontaneous induction… (More)
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Highly Cited
1993
Highly Cited
1993
We have studied transport and localization of MBP mRNA in oligodendrocytes in culture by microinjecting labeled mRNA into living… (More)
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Highly Cited
1985
Highly Cited
1985
Amino acid sequence homology was found between viral and host encephalitogenic protein. Immune responses were then generated in… (More)
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