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Myelin Associated Glycoprotein

Known as: Siglec-4, Sialic Acid Binding Ig like Lectin 4, myelin-associated glycoprotein (MAG) 
A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems myelin sheaths. It binds to cells surface… Expand
National Institutes of Health

Papers overview

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Review
2006
Review
2006
  • G. Yiu, Z. He
  • Nature Reviews Neuroscience
  • 2006
  • Corpus ID: 205500634
Damage to the adult CNS often leads to persistent deficits due to the inability of mature axons to regenerate after injury… Expand
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Highly Cited
2006
Highly Cited
2006
H5N1 influenza A viruses have spread to numerous countries in Asia, Europe and Africa, infecting not only large numbers of… Expand
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Highly Cited
2005
Highly Cited
2005
The inability of CNS axons to regenerate after traumatic spinal cord injury is due, in part, to the inhibitory effects of myelin… Expand
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Highly Cited
2004
Highly Cited
2004
Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by… Expand
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Highly Cited
2003
Highly Cited
2003
Destruction of myelin and oligodendrocytes leading to the formation of large demyelinated plaques is the hallmark of multiple… Expand
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Highly Cited
2002
Highly Cited
2002
The inhibitory activity associated with myelin is a major obstacle for successful axon regeneration in the adult mammalian… Expand
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Highly Cited
2002
Highly Cited
2002
The adult mammalian CNS has a limited capacity for nerve regeneration and structural plasticity. The presence of glia-derived… Expand
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Highly Cited
2002
Highly Cited
2002
Myelin-associated glycoprotein (MAG), an inhibitor of axon regeneration, binds with high affinity to the Nogo-66 receptor (NgR… Expand
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Highly Cited
1994
Highly Cited
1994
Following nerve injury, axons in the CNS do not normally regenerate. It has been shown that CNS myelin inhibits neurite outgrowth… Expand
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Highly Cited
1988
Highly Cited
1988
Lack of neurite growth in optic nerve explants in vitro has been suggested to be due to nonpermissive substrate properties of… Expand
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