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MutL Proteins

Known as: MutL Proteins [Chemical/Ingredient] 
DNA repair proteins that include the bacterial MutL protein and its eukaryotic homologs. They consist of a conserved N-terminal region with weak… Expand
National Institutes of Health

Papers overview

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2009
2009
Background Human PMS2 (hPMS2) homologues act to nick 5′ and 3′ to misincorporated nucleotides during mismatch repair in organisms… Expand
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Highly Cited
2006
Highly Cited
2006
Summary Half of hereditary nonpolyposis colon cancer kindreds harbor mutations that inactivate MutLα (MLH1•PMS2 heterodimer… Expand
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Highly Cited
2006
Highly Cited
2006
Half of hereditary nonpolyposis colon cancer kindreds harbor mutations that inactivate MutLalpha (MLH1*PMS2 heterodimer… Expand
Highly Cited
2004
Highly Cited
2004
We have characterized the mismatch repair system (MMR) of the highly radiation-resistant type strain of Deinococcus radiodurans… Expand
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Review
2004
Review
2004
The Saccharomyces cerevisiae mismatch repair (MMR) protein MSH6 and the SGS1 helicase were recently shown to play similarly… Expand
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Highly Cited
2003
Highly Cited
2003
The Escherichia coli MutS and MutL proteins have been conserved throughout evolution, although their combined functions in… Expand
Highly Cited
2003
Highly Cited
2003
Type IIA and type IIB topoisomerases each possess the ability to pass one DNA duplex through another in an ATP‐dependent manner… Expand
Review
2003
Review
2003
In eukaryotes, homologs of the Escherichia coli MutS and MutL proteins are crucial for both meiotic recombination and post… Expand
Highly Cited
1995
Highly Cited
1995
The MutS, MutH and MutL proteins mediate methyl-directed-mismatch (MDM) repair in Escherichia coli and Salmonella typhimurium… Expand