MutL Proteins

Known as: MutL Proteins [Chemical/Ingredient] 
DNA repair proteins that include the bacterial MutL protein and its eukaryotic homologs. They consist of a conserved N-terminal region with weak… (More)
National Institutes of Health

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2009
2009
BACKGROUND Human PMS2 (hPMS2) homologues act to nick 5' and 3' to misincorporated nucleotides during mismatch repair in organisms… (More)
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Highly Cited
2006
Highly Cited
2006
Half of hereditary nonpolyposis colon cancer kindreds harbor mutations that inactivate MutLalpha (MLH1*PMS2 heterodimer… (More)
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Highly Cited
2006
Highly Cited
2006
Summary Half of hereditary nonpolyposis colon cancer kindreds harbor mutations that inactivate MutLα (MLH1•PMS2 heterodimer… (More)
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2004
2004
We have characterized the mismatch repair system (MMR) of the highly radiation-resistant type strain of Deinococcus radiodurans… (More)
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Review
2004
Review
2004
The Saccharomyces cerevisiae mismatch repair (MMR) protein MSH6 and the SGS1 helicase were recently shown to play similarly… (More)
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Highly Cited
2003
Highly Cited
2003
The Escherichia coli MutS and MutL proteins have been conserved throughout evolution, although their combined functions in… (More)
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2003
2003
Type IIA and type IIB topoisomerases each possess the ability to pass one DNA duplex through another in an ATP-dependent manner… (More)
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Review
2003
Review
2003
In eukaryotes, homologs of the Escherichia coli MutS and MutL proteins are crucial for both meiotic recombination and post… (More)
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1995
1995
The MutS, MutH and MutL proteins mediate methyl-directed-mismatch (MDM) repair in Escherichia coli and Salmonella typhimurium… (More)
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