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Mucin-5B

Known as: High Molecular Weight Salivary Mucin MG1, Mucin 5B, Mucin-5 Subtype B, Tracheobronchial 
A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal… Expand
National Institutes of Health

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In BloodMUC5B geneProcess of secretionagonists
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MUC5B protein, human

Papers overview

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2017
2017
Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers
BACKGROUND: Smoking‐related lung injury may manifest on CT scans as both emphysema and interstitial changes. We have developed an… Expand
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2017
2017
Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis
&NA; The gain‐of‐function mucin 5B (MUC5B) promoter variant, rs35705950, confers the largest risk, genetic or otherwise, for the… Expand
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2015
2015
MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis.
BACKGROUND AND OBJECTIVE A single nucleotide polymorphism (SNP) rs35705950 in the promoter of Mucin 5B (MUC5B) has been reported… Expand
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2015
2015
Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells.
BACKGROUND Balanced activation and inhibition of the immune system ensures pathogen clearance while avoiding hyperinflammation… Expand
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2014
2014
Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations
BACKGROUND Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing… Expand
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2013
2013
Analysis of factors influencing the development of xerostomia during intensity-modulated radiotherapy.
OBJECTIVES Factors influencing xerostomia during intensity-modulated radiation therapy (IMRT) were assessed. METHODS A 6-week… Expand
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2013
2013
Aberrant Mucin5B expression in lung adenocarcinomas detected by iTRAQ labeling quantitative proteomics and immunohistochemistry
BackgroundLung cancer is the number one cause of cancer-related deaths in the United States and worldwide. The complex protein… Expand
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2009
2009
HSP70 and mucin 5B: novel protein targets of N,N'-dinitrosopiperazine-induced nasopharyngeal tumorigenesis.
N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyngeal… Expand
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2007
2007
Distinctive epidermal growth factor receptor/extracellular regulated kinase-independent and -dependent signaling pathways in the induction of airway mucin 5B and mucin 5AC expression by phorbol 12…
Elevated expression of gel-forming mucin (MUC) genes MUC5AC and MUC5B is a major pathological feature in various airway diseases… Expand
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2007
2007
Upper airway mucus deposition in lung tissue of burn trauma victims.
Previous study in an ovine model of smoke inhalation and burn (S + B) injury has shown distal migration of upper airway mucus… Expand
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