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Mucin-1 protein

Known as: Mucin, Episialin, CD227 Antigen 
Mucin-1 (1255 aa, ~122 kDa) is encoded by the human MUC1 gene. This protein plays a role in both signaling and cell adhesion.
National Institutes of Health

Related topics

Related topics

10 relations
Binding ProteinsCA 15-3 measurementCell AdhesionLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Positron Emission Mammography: Initial Clinical Results
Background: Evaluation of high-risk mammograms represents an enormous clinical challenge. Functional breast imaging coupled with… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of the cytoplasmic domain of the MUC1 mucin correlates with changes in cell‐cell adhesion
The MUC1 epithelial mucin is expressed by glandular epithelial cells and is often highly expressed and associated with poor… 
Highly Cited
1998
Highly Cited
1998
Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines.
Two breast cancer cell lines, YMB-S and ZR-75-1S, were established in our laboratory. They proliferated in suspension culture… 
Highly Cited
1998
Highly Cited
1998
Enhanced binding of antibodies to the DTR motif of MUC1 tandem repeat peptide is mediated by site-specific glycosylation.
The epithelial mucin MUC1 is an important tumor marker of breast cancer and other carcinomas. Its immunodominant DTR motif, which… 
Highly Cited
1997
Highly Cited
1997
Immunodetection of epithelial mucin (MUC1, MUC3) and mucin-associated glycotopes (TF, Tn, and sialosyl-Tn) in benign and malignant lesions of colonic epithelium: apolar localization corresponds to…
Abstract Epithelial mucins are present at the apical membranes of gastrointestinal epithelial cells or in their secretions. In… 
Highly Cited
1996
Highly Cited
1996
Effect of fibronectin amount and conformation on the strength of endothelial cell adhesion to HEMA/EMA copolymers.
The effect of substrate surface hydrophobicity on fibronectin (Fn) adsorption and endothelial cell adhesion strength was studied… 
Highly Cited
1996
Highly Cited
1996
Detection of a secreted MUC1/SEC protein by MUC1 isoform specific monoclonal antibodies.
Although MUC1 proteins are known to be secreted by breast cancer cells, the mechanism of their release from the cell is still… 
Review
1995
Review
1995
Is episialin/MUC1 involved in breast cancer progression?
Highly Cited
1991
Highly Cited
1991
Evidence for different human tracheobronchial mucin peptides deduced from nucleotide cDNA sequences.
Highly glycosylated regions or glycopeptides were obtained by proteolysis of human tracheobronchial mucins. They were chemically… 
Highly Cited
1974
Highly Cited
1974
Copulatory behavior of male rats given intermittent electric shocks: theoretical implications.
In 3 experiments mildly painful .5-sec. shocks, delivered to the skin of male rats every 30 sec. in the presence of a receptive… 
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