Motor neuron atrophy

Known as: Motor neuron degeneration 
Wasting involving the motor neuron. [HPO:probinson]
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Defective RNA metabolism is an emerging mechanism involved in ALS pathogenesis and possibly in other neurodegenerative disorders… (More)
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Highly Cited
2005
Highly Cited
2005
Heat-shock protein 90 (Hsp90) functions as part of a multichaperone complex that folds, activates and assembles its client… (More)
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Review
2004
Review
2004
Although Charcot described amyotrophic lateral sclerosis (ALS) more than 130 years ago, the mechanism underlying the… (More)
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Highly Cited
2003
Highly Cited
2003
Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS… (More)
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Highly Cited
2002
Highly Cited
2002
To test the hypothesis that inhibition of axonal transport is sufficient to cause motor neuron degeneration such as that observed… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia stimulates angiogenesis through the binding of hypoxia-inducible factors to the hypoxia-response element in the vascular… (More)
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Highly Cited
1998
Highly Cited
1998
Amyotrophic lateral sclerosis (ALS) involves motor neuron degeneration, skeletal muscle atrophy, paralysis, and death. Mutations… (More)
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Highly Cited
1995
Highly Cited
1995
Ciliary neurotrophic factor (CNTF) supports motor neuron survival in vitro and in mouse models of motor neuron degeneration and… (More)
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Highly Cited
1993
Highly Cited
1993
CNTF is a cytosolic molecule expressed postnatally in myelinating Schwann cells and in a sub-population of astrocytes. Although… (More)
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Highly Cited
1992
Highly Cited
1992
CILIARY neurotrophic factor (CNTF) supports the survival of embryonic motor neurons in vitro1,2 and in vivo3, and prevents lesion… (More)
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