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Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial

Known as: EC 6.3.4.3, Formyltetrahydrofolate Synthetase 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (978 aa, ~106 kDa) is encoded by the human MTHFD1L gene. This protein is involved in the… 
National Institutes of Health

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Enzyme GeneFormate-Tetrahydrofolate LigaseFumarate Hydratase, Mitochondrial, humanHomo sapiens

Papers overview

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2016
2016
Function of yeast cytoplasmic Cl-tetrahydrofolate synthase (Saccharomyces cerevisiae/heterologous gene expression/ADE3/purine biosynthesis)
The protein product of the ADE3 gene of the yeast Saccharomyces cerevisiae has been identified as the cy- toplasmic trifunctional… 
2012
2012
Methanogen Colonisation Does Not Significantly Alter Acetogen Diversity in Lambs Isolated 17 h After Birth and Raised Aseptically
Reductive acetogenesis is not competitive with methanogenesis in adult ruminants, whereas acetogenic bacteria are the dominant… 
1986
1986
Activity of formylphosphate in the reaction catalyzed by formyltetrahydrofolate synthetase
Formylphosphate (FP), a putative enzyme-bound intermediate in the reaction catalyzed by N/sup 10/-formylH/sub 4/folate synthetase… 
1985
1985
In vitro synthesis of the trifunctional protein, methylenetetrahydrofolate dehydrogenase--methenyltetrahydrofolate cyclohydrolase--formyltetrahydrofolate synthetase, in normal and transformed cells.
The trifunctional eucaryotic protein, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase… 
Highly Cited
1972
Highly Cited
1972
Formyltetrahydrofolate synthetase. Binding of folate substrates and kinetics of the reverse reaction.
Abstract During the fermentation of purines by Clostridium acidi-urici and Clostridium cylindrosporum, formyltetrahydrofolate… 
1970
1970
Effects of thyroxine on the synthesis of folate coenzymes in rat liver.
1. The effects of thyroidectomy and of ;acute' and ;chronic' administration of thyroxine on the synthesis of folate coenzymes… 
1966
1966
Formyltetrahydrofolate synthetase. Initial velocity and product inhibition studies.
Abstract The order of binding of the substrates to formyltetrahydrofolate synthetase from Clostridium cylindrosporum was examined… 
1962
1962
Formyltetrahydrofolate synthetase. III. Studies on the mechanism of the reaction.