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Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial
Known as:
EC 6.3.4.3
, Formyltetrahydrofolate Synthetase
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (978 aa, ~106 kDa) is encoded by the human MTHFD1L gene. This protein is involved in the…
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National Institutes of Health
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Related topics
Related topics
8 relations
Enzyme Gene
Formate-Tetrahydrofolate Ligase
Fumarate Hydratase, Mitochondrial, human
Homo sapiens
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation
S. Sdelci
,
André F. Rendeiro
,
+34 authors
S. Kubicek
Nature Genetics
2019
Corpus ID: 167208534
The histone acetyl reader bromodomain-containing protein 4 (BRD4) is an important regulator of chromatin structure and…
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2016
2016
Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
K. Christensen
,
Wenyang Hou
,
+7 authors
R. Rozen
The American journal of clinical nutrition
2016
Corpus ID: 42035125
BACKGROUND Moderately high folic acid intake in pregnant women has led to concerns about deleterious effects on the mother and…
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2015
2015
Hydrogenotrophic culture enrichment reveals rumen Lachnospiraceae and Ruminococcaceae acetogens and hydrogen-responsive Bacteroidetes from pasture-fed cattle.
E. Gagen
,
J. Padmanabha
,
S. Denman
,
C. McSweeney
FEMS microbiology letters
2015
Corpus ID: 13932644
Molecular information suggests that there is a broad diversity of acetogens in the rumen, distinct from any currently isolated…
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2014
2014
Investigation of a new acetogen isolated from an enrichment of the tammar wallaby forestomach
E. Gagen
,
Jiakun Wang
,
+8 authors
C. McSweeney
BMC Microbiology
2014
Corpus ID: 12433452
BackgroundForestomach fermentation in Australian marsupials such as wallabies and kangaroos, though analogous to rumen…
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2012
2012
Methanogen Colonisation Does Not Significantly Alter Acetogen Diversity in Lambs Isolated 17 h After Birth and Raised Aseptically
E. Gagen
,
P. Mosoni
,
S. Denman
,
R. Jassim
,
C. McSweeney
,
E. Forano
Microbial Ecology
2012
Corpus ID: 8692547
Reductive acetogenesis is not competitive with methanogenesis in adult ruminants, whereas acetogenic bacteria are the dominant…
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2012
2012
The role of homoacetogenic bacteria as efficient hydrogen scavengers in microbial electrochemical cells (MXCs).
P. Parameswaran
,
César I. Torres
,
Dae-Wook Kang
,
B. Rittmann
,
R. Krajmalnik-Brown
Water science and technology : a journal of the…
2012
Corpus ID: 21075894
We evaluated the consumption of hydrogen gas at the anode of a microbial electrolysis cell (MEC) and characterized the…
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Review
2008
Review
2008
Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases.
K. Christensen
,
R. Mackenzie
Vitamins and hormones
2008
Corpus ID: 21043949
1993
1993
Function of yeast cytoplasmic C1-tetrahydrofolate synthase.
J. M. Song
,
J. Rabinowitz
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 627700
The protein product of the ADE3 gene of the yeast Saccharomyces cerevisiae has been identified as the cytoplasmic trifunctional…
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Highly Cited
1972
Highly Cited
1972
Formyltetrahydrofolate synthetase. Binding of folate substrates and kinetics of the reverse reaction.
N. Curthoys
,
J. Rabinowitz
The Journal of biological chemistry
1972
Corpus ID: 19890373
Abstract During the fermentation of purines by Clostridium acidi-urici and Clostridium cylindrosporum, formyltetrahydrofolate…
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1970
1970
Dietary regulation of glycolytic enzymes. VII. Effect of diet and oral folate upon folate-metabolizing enzymes in rat jejunum.
F. Stifel
,
R. Herman
,
N. Rosensweig
Biochimica et biophysica acta
1970
Corpus ID: 40640210
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