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Monoclonal T-cell Receptor Anti-CD3 scFv Fusion Protein IMCgp100
Known as:
IMCgp100
, ImmTAC-gp100
A fusion protein containing a modified form of human T-cell receptor (TCR) specific for the gp100 antigen and fused to an anti-CD3 single-chain…
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National Institutes of Health
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1 relation
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract A214: An in vitro preclinical package to assess the safety and efficacy of ImmTAC™ molecules
Ana Ribeiro
,
Tomasz Dobrzycki
,
+14 authors
J. Dukes
Regulating T-cells and Their Response to Cancer
2019
Corpus ID: 86486124
Immune Mobilising Monoclonal TCRs Against Cancer (ImmTAC) molecules are a new class of bi-specific biologic specifically designed…
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2017
2017
Abstract 3655: Biomarker strategy to guide the clinical development of ImmTACTMmolecules, a novel class of bispecific T cell engaging biologic drugs
C. McAlpine
,
D. Krige
,
+9 authors
B. Jakobsen
2017
Corpus ID: 80422455
IMCgp100, a first in class immunotherapy, is a T cell redirecting bispecific biologic comprising an affinity enhanced T-cell…
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2017
2017
Abstract A35: Biomarker Strategy To Guide Clinical Development Of ImmTAC™ molecules , A Novel Class Of Bispecific T Cell Engaging Biologic Drugs
C. McAlpine
,
S. Gonzalez
,
+8 authors
B. Jakobsen
2017
Corpus ID: 79185332
IMCgp100, a first in class immunotherapy, is a T cell redirecting bispecific biologic comprising an affinity enhanced T-cell…
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2016
2016
Abstract A037: IMCgp100 ImmTAC: A new immunotherapeutic reagent for the treatment of malignant melanoma
J. Pentier
,
M. Connolly
,
+5 authors
B. Jakobsen
2016
Corpus ID: 77346710
For years cancer therapies were mainly concentrated around surgery, chemotherapy and radiotherapy. Recently, a new domain has…
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2016
2016
Abstract 4873: ImmTACs re-direct the immune system efficiently to eradicate cancer
G. Bossi
,
R. Kenefeck
,
+12 authors
B. Jakobsen
2016
Corpus ID: 78269360
Immunotherapy strategies that are able to induce T cell infiltration into tumors and activate a cytotoxic T cell response have…
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2015
2015
BEAM to fight antimicrobial resistance
Nature Biotechnology
2015
Corpus ID: 8646698
Immunocore of Abingdon, UK, secured a record $320 million in a series A round in July. It is Europe’s largest-ever venture round…
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2015
2015
UK biotech smashes financing record
Nature Biotechnology
2015
Corpus ID: 10587009
Immunocore of Abingdon, UK, secured a record $320 million in a series A round in July. It is Europe’s largest-ever venture round…
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2013
2013
IMCgp100: a novel bispecific biologic for the treatment of malignant melanoma.
M. Middleton
,
J. Evans
,
+12 authors
B. Jakobsen
2013
Corpus ID: 220663584