Mitox
National Institutes of Health
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Chapter A: Introduction on supramolecular gels and application of gels in drug release
The first section (chapter B1) presents…
Glioblastoma is a highly malignant and aggressive high grade glioma with a poor prognosis. The low survival rates stem from…
BACKGROUND
Mitoxantrone resistance has been related to the expression of a drug efflux pump breast cancer resistance pump (BCRP…
Therapeutic strategies for combating HIV-associated lipodystrophy, and lipoatrophy in particular, have been a major focus of HIV…
Sensitization of leukemic cells with GM-CSF may enhance the cytotoxicity of chemotherapy in younger adults with newly diagnosed…
In addition to its action as a topoisomerase II poison, mitoxantrone is activated by formaldehyde to bind DNA, forming DNA…
We report a case of therapy-related acute myeloid leukemia (t-AML), M4 FAB subtype, with t(10;11)(p14;q21) chromosome abnormality…
In an effort to synthesize drugs which would become much more cytotoxic at clinically achievable hyperthermic temperatures…
In a multi-institutional study 26 patients with refractory acute myeloid leukemia were entered into a phase I/II study of HD-ara…
Based on the promising results of monotherapy trials with HD-AraC and Mitox. in refractory AML a multi-institutional study was…