Mitotic Sister Chromatid Cohesion
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Most solid tumors are aneuploid, having a chromosome number that is not a multiple of the haploid number, and many frequently mis… Expand Aneuploidy arising early in development is the leading genetic cause of birth defects and developmental disabilities in humans… Expand Much of the complex process of RNP biogenesis takes place at the gene cotranscriptionally. The target for RNA binding and… Expand In eukaryotes, diploid cells give rise to haploid cells via meiosis, a program of two cell divisions preceded by one round of DNA… Expand In vertebrate mitosis, cohesion between sister chromatids is lost in two stages. In prophase and prometaphase, cohesin release… Expand Abnormal chromosome content — also known as aneuploidy — is the most common characteristic of human solid tumours. It has… Expand Studies of human oocytes obtained from women of advanced reproductive age revealed that spindles are frequently aberrant, with… Expand The faithful transmission of chromosomes during mitosis and meiosis requires the establishment and subsequent release of cohesion… Expand The mechanism of prokaryotic chromosome segregation is not known. MreB, an actin homolog, is a shape‐determining factor in rod… Expand In S. cerevisiae, posttranslational modification by the ubiquitin-like Smt3/SUMO-1 protein is essential for survival, but… Expand