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Mitogen-Activated Protein Kinase Kinases

Known as: Mitogen-Activated Protein Kinase Kinase, Mitogen Activated Protein Kinase Kinases, Kinase Kinase, Map 
A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The MAPK pathway is one of the most commonly mutated oncogenic pathways in cancer. Although RAS mutations are the most frequent… Expand
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Review
2019
Review
2019
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common age-related neurodegenerative disorders, affecting… Expand
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Highly Cited
2001
Highly Cited
2001
TRAF6 is a signal transducer that activates IκB kinase (IKK) and Jun amino-terminal kinase (JNK) in response to pro-inflammatory… Expand
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Highly Cited
2000
Highly Cited
2000
Despite the recognition of H(2)O(2) as a central signaling molecule in stress and wounding responses, pathogen defense, and… Expand
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Highly Cited
1998
Highly Cited
1998
The compound U0126 (1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene) was identified as an inhibitor of AP-1… Expand
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Review
1998
Review
1998
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase (MAPK) module. The identification of MAP… Expand
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Highly Cited
1996
Highly Cited
1996
The mitogen-activated protein kinase (MAPK) family is comprised of key regulatory proteins that control the cellular response to… Expand
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Highly Cited
1995
Highly Cited
1995
PD 098059 has been shown previously to inhibit the dephosphorylated form of mitogen-activated protein kinase kinase-1 (MAPKK1… Expand
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Highly Cited
1995
Highly Cited
1995
Mammalian mitogen-activated protein (MAP) kinases include extracellular signal-regulated protein kinase (ERK), c-Jun amino… Expand
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Highly Cited
1994
Highly Cited
1994
Mitogen-activated protein (MAP) kinase kinase (MAPKK) activates MAP kinase in a signal transduction pathway that mediates… Expand
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