Mitogen-Activated Protein Kinase Inhibitor

Known as: MAPK Inhibitors 
Any substance that inhibits mitogen-activated protein kinase (MAPK), an enzyme that catalyzes the addition of a phosphate group to a protein in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
05101519972017

Papers overview

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2008
2008
P38alpha is a protein kinase that regulates the expression of inflammatory cytokines, suggesting a role in the pathogenesis of… (More)
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Highly Cited
2007
Highly Cited
2007
Previous studies have shown that raising cytosolic calcium in myotubes induces increases in peroxisome proliferator-activated… (More)
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2007
2007
In the oral microbial environment, Gram-negative bacterial derived lipopolysaccharide (LPS) can initiate inflammatory bone loss… (More)
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2006
2006
Destruction of cartilage and bone is a poorly managed hallmark of human rheumatoid arthritis (RA). p38 Mitogen-activated protein… (More)
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2005
2005
The translocation of glucose transporter-4 (GLUT4) to the cell surface is a complex multistep process that involves movement of… (More)
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2004
2004
The aryl hydrocarbon receptor (AhR) is involved in various processes such as cytochrome P450 (P450) 1A induction after xenobiotic… (More)
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2002
2002
It is widely acknowledged that mitochondrial Ca2+ uptake modulates the cytosolic [Ca2+] ([Ca2+]c) acting as a transient Ca2… (More)
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Highly Cited
2001
Highly Cited
2001
The stress-activated mitogen-activated protein kinase (MAPK) p38 has been linked to the production of inflammatory cytokines… (More)
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2001
2001
FR167653 was discovered as a cytokine production inhibitor, but its target molecule has remained unclear. We examined the effect… (More)
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1999
1999
SB203580 (4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imi dazole) is widely used as a specific inhibitor of p38… (More)
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