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Mitogen Activated Protein Kinase 1

Known as: p42(Mapk), MAPK2 Mitogen-Activated Protein Kinase, MAPK 1 
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme… 
National Institutes of Health

Related topics

Related topics

50 relations
Agrin PathwayAxon GuidanceB Cell Receptor Signaling PathwayBMP Receptor Signaling Pathway

Broader (3)

Calcium-Calmodulin-Dependent Protein KinasesCalcium/calmodulin-dependent protein kinaseProtein Tyrosine Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Testicular Lumicrine Factors Regulate ERK, STAT, and NFKB Pathways in the Initial Segment of the Rat Epididymis to Prevent Apoptosis1
The initial segment of the epididymis is vital for male fertility; therefore, it is important to understand the mechanisms that… 
2010
2010
Highly specific capture and direct MALDI MS analysis of phosphopeptides by zirconium phosphonate on self-assembled monolayers.
The dynamic range and low stoichiometry of protein phosphorylation frequently demands the enrichment of phosphorylated peptides… 
Highly Cited
2008
Highly Cited
2008
Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans
To gain a better understanding of the genetic variants associated with carboplatin-induced cytotoxicity in individuals of African… 
2003
2003
Mapping of Synergistic Components of Weakly Interacting Protein-Protein Motifs Using Arrays of Paired Peptides*
Protein-protein recognition usually involves multiple interactions among different motifs that are scattered over protein… 
2002
2002
YIL113w encodes a functional dual‐specificity protein phosphatase which specifically interacts with and inactivates the Slt2/Mpk1p MAP kinase in S. cerevisiae
2001
2001
Differences in signal transduction pathways by which platelet‐derived and fibroblast growth factors activate extracellular signal‐regulated kinase in differentiating oligodendrocytes
Treatment of cultured rat oligodendroglial progenitors with either platelet‐derived growth factor (PDGF) or fibroblast growth… 
1999
1999
Distinct, constitutively active MAPK phosphatases function in Xenopus oocytes: implications for p42 MAPK regulation In vivo.
Xenopus oocyte maturation requires the phosphorylation and activation of p42 mitogen-activated protein kinase (MAPK). Likewise… 
1999
1999
Protein kinase C mediates basic fibroblast growth factor-induced proliferation through mitogen-activated protein kinase in coronary smooth muscle cells.
Proliferation of coronary smooth muscle cells (cSMCs) contributes to the pathogenesis of arteriosclerosis and restenosis after… 
Highly Cited
1998
Highly Cited
1998
Activation of the p42 mitogen-activated protein kinase pathway inhibits Cdc2 activation and entry into M-phase in cycling Xenopus egg extracts.
We have added constitutively active MAP kinase/ERK kinase (MEK), an activator of the mitogen-activated protein kinase (MAPK… 
1997
1997
gp160 of HIV or anti‐CD4 monoclonal antibody ligation of CD4 induces inhibition of JNK and ERK‐2 activities in human peripheral CD4+ T lymphocytes
Under physiological conditions, activation of CD4+ T cells by major histocom‐patibility complex (MHC) antigen complexes requires… 
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