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Mitochondrial Replacement Therapy

Known as: Therapy, Mitochondrial Replacement, Spindle Transfer Technique, Therapies, Mitochondrial Replacement 
In vitro fertilization technique that uses mitochondrial DNA from a healthy donor in order to prevent the transmission of MITOCHONDRIAL DISEASE.
National Institutes of Health

Related topics

Related topics

3 relations
legislation & jurisprudencenursing therapystandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Should mitochondrial replacement therapy be funded by the National Health Service?
A clinical trial on mitochondrial replacement therapy (MRT) is currently being conducted and if this technique proves effective… 
2020
2020
It Is Time to Consult the Children: A Mother Who Faced Mitochondrial Replacement and Her Son Consider the Limits of Genetic Modification
Debate over the ethics of genetic modification of children born using In Vitro Fertilization (IVF) and other reproductive… 
Review
2019
Review
2019
Heteroplasmy Shifting as Therapy for Mitochondrial Disorders.
Mitochondrial disease can arise due to pathogenic sequence variants in the mitochondrial DNA (mtDNA) that prevent cells from… 
Review
2019
Review
2019
Advances Towards Therapeutic Approaches for mtDNA Disease.
Mitochondria maintain and express their own genome, referred to as mtDNA, which is required for proper mitochondrial function… 
2017
2017
Response: First birth following spindle transfer.
2017
2017
Mitochondrial replacement therapy and ‘three‐parent children’—who should be registered as the legal parents?
CELIA BURRELL, CONSULTANT OBSTETRICIAN AND OBSTETRIC LEAD FOR RISK MANAGEMENT, BHRUT NHS TRUST, UK… 
2016
2016
Mitchochondrial replacement therapy: the IOM report and its aftermath
Glenn Cohen and Eli Adashi comment on the recommendations and limitations of the Institute of Medicine (IOM) report on… 
2016
2016
The first clinical nuclear transplantation in China: new information about a case reported to ASRM in 2003.
Review
2016
Review
2016
CRISPR / Cas 9 and mitochondrial gene replacement therapy : promising techniques and ethical considerations
Thousands of mothers are at risk of transmitting mitochondrial diseases to their offspring each year, with the most severe form… 
2011
2011
Changes in the activity of defense mechanisms against induced acidosis during meiotic maturation in mouse oocytes.
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