Mitochondrial Malate Dehydrogenase, human

Known as: EC 1.1.1.37, MDH2, Malate Dehydrogenase, Mitochondrial 
Malate dehydrogenase, mitochondrial (338 aa, ~36 kDa) is encoded by the human MDH2 gene. This protein plays a role in the conversion of malate to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Disruption of the Krebs cycle is a hallmark of cancer. IDH1 and IDH2 mutations are found in many neoplasms, and germline… Expand
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2014
2014
Doxorubicin is a highly effective anticancer chemotherapy agent, but its use is limited by its cardiotoxicity. To develop a drug… Expand
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Highly Cited
2013
Highly Cited
2013
The MYC genes are the most frequently activated oncogenes in human tumors and are hence attractive therapeutic targets. MYCN… Expand
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2012
2012
Cisplatin is used widely for treatment of a variety of cancer diseases. Recently, however, the use of cisplatin is restricted… Expand
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Highly Cited
2006
Highly Cited
2006
Ulcerative colitis (UC) is a chronic inflammatory disorder primarily affecting the colon mucosa. Its etiology and pathogenesis… Expand
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2004
2004
The key gluconeogenic enzyme fructose-1,6-bisphosphatase (FBPase) is subjected to catabolite inactivation and degradation when… Expand
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2001
2001
Malate dehydrogenase isoenzymes are localized in different cellular compartments and fulfil important functions in intermediary… Expand
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1997
1997
Quinone redox cycling is generally known as an intracellular process that implies the reduction of quinones (Q) into semiquinones… Expand
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1992
1992
The MDH3 isozyme of Saccharomyces cerevisiae was purified from a haploid strain containing disruptions in genomic loci encoding… Expand
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1991
1991
The major nonmitochondrial isozyme of malate dehydrogenase (MDH2) in Saccharomyces cerevisiae cells grown with acetate as a… Expand
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