Mitochondrial Degradation

Known as: Degradation, Mitochondrial, Mitophagy, mitochondrion autophagy 
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions. [GOC:autophagy… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are… (More)
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Review
2017
Review
2017
Neuronal homeostasis depends on the proper functioning of different quality control systems. All intracellular components are… (More)
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Highly Cited
2011
Highly Cited
2011
Upon mitochondrial depolarization, Parkin, a Parkinson disease-related E3 ubiquitin ligase, translocates from the cytosol to… (More)
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Highly Cited
2010
Highly Cited
2010
Parkinson's disease (PD) is a prevalent neurodegenerative disorder. Recent identification of genes linked to familial forms of PD… (More)
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Highly Cited
2010
Highly Cited
2010
Damage to mitochondria can lead to the depolarization of the inner mitochondrial membrane, thereby sensitizing impaired… (More)
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Highly Cited
2010
Highly Cited
2010
PINK1 is a mitochondrial kinase mutated in some familial cases of Parkinson's disease. It has been found to work in the same… (More)
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Highly Cited
2010
Highly Cited
2010
Loss of the E3 ubiquitin ligase Parkin causes early onset Parkinson's disease, a neurodegenerative disorder of unknown etiology… (More)
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Highly Cited
2009
Highly Cited
2009
Mitochondrial dysregulation is strongly implicated in Parkinson disease. Mutations in PTEN-induced kinase 1 (PINK1) are… (More)
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Highly Cited
2009
Highly Cited
2009
Mitochondrial quality control is important in maintaining proper cellular homeostasis. Although selective mitochondrial… (More)
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Highly Cited
2005
Highly Cited
2005
In autophagy, portions of cytoplasm are sequestered into autophagosomes and delivered to lysosomes for degradation. Long assumed… (More)
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