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Mirvetuximab Soravtansine

An immunoconjugate consisting of the humanized monoclonal antibody M9346A against folate receptor 1 (FOLR1) conjugated, via the disulfide-containing… Expand
National Institutes of Health

Papers overview

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2018
2018
Mirvetuximab soravtansine, an antibody-drug conjugate that binds with high affinity to folate receptor-α to provide tumor… Expand
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2018
2018
PURPOSE To evaluate the safety profile and preliminary antitumor activity of mirvetuximab soravtansine when administered in… Expand
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Highly Cited
2017
Highly Cited
2017
Purpose This phase I expansion cohort study evaluated the safety and clinical activity of mirvetuximab soravtansine (IMGN853), an… Expand
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2017
2017
BACKGROUND Mirvetuximab soravtansine (IMGN853) is an antibody-drug conjugate that selectively targets folate receptor α (FRα). In… Expand
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2017
2017
Purpose. To characterize folate receptor alpha (FRα) expression in archival and fresh biopsy tumor samples from relapsed ovarian… Expand
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2017
2017
5553Background: FORWARD II is a phase 1b study of the FRα-targeting ADC, mirvetuximab soravtansine (IMGN853), in combination with… Expand
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2017
2017
5547Background: The early clinical evaluation of mirvetuximab soravtansine (IMGN853), an ADC that comprises a FRα-binding… Expand
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2016
2016
Elevated folate receptor alpha (FRα) expression is characteristic of epithelial ovarian cancer (EOC), thus establishing this… Expand
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2015
2015
Background: IMGN853 is a FRα-targeting ADC comprising a FRα-binding antibody conjugated with the potent maytansinoid, DM4, a… Expand
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