Microtubule-Associated Proteins 1A/1B Light Chain 3-II

Known as: LC3-II, MAP1LC3-II 
Microtubule-associated proteins 1A/1B light chain 3-II proteins (LC3-II) are products of the autophagy-dependent processing of microtubule-associated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
010020030020002018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Disturbance to endoplasmic reticulum (ER) homeostasis that cannot be rescued by the unfolded protein response (UPR) results in… (More)
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Highly Cited
2009
Highly Cited
2009
Macroautophagy is a process that leads to the bulk degradation of subcellular constituents by producing autophagosomes… (More)
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Highly Cited
2009
Highly Cited
2009
The Hsc/Hsp70 co-chaperones of the BAG (Bcl-2-associated athanogene) protein family are modulators of protein quality control. We… (More)
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Highly Cited
2008
Highly Cited
2008
Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's… (More)
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Highly Cited
2007
Highly Cited
2007
Several types of cancer cells, including colorectal cancer-derived cell lines, show austerity, the resistance to nutrient… (More)
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Highly Cited
2006
Highly Cited
2006
Eukaryotic cells deal with accumulation of unfolded proteins in the endoplasmic reticulum (ER) by the unfolded protein response… (More)
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Highly Cited
2005
Highly Cited
2005
Mammalian cells were observed to die under conditions in which nutrients were depleted and, simultaneously, macroautophagy was… (More)
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Highly Cited
2005
Highly Cited
2005
During starvation-induced autophagy in mammals, autophagosomes form and fuse with lysosomes, leading to the degradation of the… (More)
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Highly Cited
2004
Highly Cited
2004
Rat LC3, a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The… (More)
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Highly Cited
2000
Highly Cited
2000
Little is known about the protein constituents of autophagosome membranes in mammalian cells. Here we demonstrate that the rat… (More)
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