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Microtubule-Associated Proteins 1A/1B Light Chain 3-II

Known as: LC3-II, MAP1LC3-II 
Microtubule-associated proteins 1A/1B light chain 3-II proteins (LC3-II) are products of the autophagy-dependent processing of microtubule-associated… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
VCP (VCP/p97) is a ubiquitously expressed member of the AAA(+)-ATPase family of chaperone-like proteins that regulates numerous… Expand
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Highly Cited
2010
Highly Cited
2010
Disturbance to endoplasmic reticulum (ER) homeostasis that cannot be rescued by the unfolded protein response (UPR) results in… Expand
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Highly Cited
2008
Highly Cited
2008
Microtubule-associated protein 1A/1B-light chain 3 (LC3) is a soluble protein with a molecular mass of approximately 17 kDa that… Expand
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Highly Cited
2008
Highly Cited
2008
Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's… Expand
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Highly Cited
2008
Highly Cited
2008
It has been reported that ischemic insult increases the formation of autophagosomes and activates autophagy. However, the role of… Expand
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Review
2007
Review
2007
Microtubule-associated protein light chain 3 (LC3) is now widely used to monitor autophagy. One approach is to detect LC3… Expand
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Highly Cited
2006
Highly Cited
2006
Eukaryotic cells deal with accumulation of unfolded proteins in the endoplasmic reticulum (ER) by the unfolded protein response… Expand
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Highly Cited
2005
Highly Cited
2005
During starvation-induced autophagy in mammals, autophagosomes form and fuse with lysosomes, leading to the degradation of the… Expand
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Highly Cited
2004
Highly Cited
2004
Rat LC3, a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The… Expand
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Highly Cited
2000
Highly Cited
2000
Little is known about the protein constituents of autophagosome membranes in mammalian cells. Here we demonstrate that the rat… Expand
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