Microbicides, Topical

Known as: Microbicides, Local, topical microbicide, topical microbicides 
Generically, any topical agent that destroys microbes. However, usage of the term is increasingly being confined to topical agents that prevent or… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Women comprise almost 50% of the population of people living with HIV and the majority of these women contracted the virus… (More)
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Highly Cited
2009
Highly Cited
2009
To prevent sexually transmitted HIV, the most desirable active ingredients of microbicides are antiretrovirals (ARVs) that… (More)
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Highly Cited
2007
Highly Cited
2007
A human cervical explant culture was utilized for the preclinical assessment of anti-human immunodeficiency virus type 1 (HIV-1… (More)
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Highly Cited
2005
Highly Cited
2005
A human colorectal explant culture was developed to assess the safety and efficacy of topical microbicides proposed for use in… (More)
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2005
2005
SPL7013 is a dendrimer with a polyanionic outer surface that allows multiple interactions with target sites. It potently binds… (More)
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Highly Cited
2004
Highly Cited
2004
A standardized protocol was used to compare cellular toxicities and anti-human immunodeficiency virus type 1 (HIV-1) activities… (More)
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2004
2004
Topical microbicides designed to prevent acquisition of sexually transmitted infections are urgently needed. Nonoxynol-9, the… (More)
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Highly Cited
2003
Highly Cited
2003
Cyanovirin-N (CV-N), an 11-kDa cyanobacterial protein, potently inactivates diverse strains of HIV-1, HIV-2, and simian… (More)
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Highly Cited
2003
Highly Cited
2003
A topical microbicide reduces the probability of virus transmission when applied to the vagina or rectum of a person at risk of… (More)
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2000
2000
Dendrimers are large highly branched macromolecules synthesized from a polyfunctional core. They have shown a variety of… (More)
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