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Mice, Inbred mdx

Known as: mdx Mouse, Inbred mdx Mice, Inbred mdx Mouse 
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Frame-disrupting mutations in the DMD gene, encoding dystrophin, compromise myofiber integrity and drive muscle deterioration in… Expand
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Highly Cited
2016
Highly Cited
2016
Duchenne muscular dystrophy (DMD) is a devastating disease affecting about 1 out of 5000 male births and caused by mutations in… Expand
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Highly Cited
2002
Highly Cited
2002
Mice and cattle with mutations in the myostatin (GDF8) gene show a marked increase in body weight and muscle mass, indicating… Expand
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Highly Cited
2000
Highly Cited
2000
Several recent studies suggest the isolation of stem cells in skeletal muscle, but the functional properties of these muscle… Expand
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Highly Cited
1999
Highly Cited
1999
The development of cell or gene therapies for diseases involving cells that are widely distributed throughout the body has been… Expand
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Highly Cited
1998
Highly Cited
1998
Duchenne muscular dystrophy (DMD) is a lethal, progressive muscle wasting disease caused by a loss of sarcolemmal bound… Expand
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Highly Cited
1993
Highly Cited
1993
The protein dystrophin, normally found on the cytoplasmic surface of skeletal muscle cell membranes, is absent in patients with… Expand
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Highly Cited
1991
Highly Cited
1991
ALTHOUGH murine X-linked muscular dystrophy (mdx) and Duchenne muscular dystrophy (DMD) are genetically homologous and both… Expand
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Highly Cited
1989
Highly Cited
1989
The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne muscular dystrophy. In both mouse and man the… Expand
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Highly Cited
1987
Highly Cited
1987
The protein product of the human Duchenne muscular dystrophy locus (DMD) and its mouse homolog (mDMD) have been identified by… Expand
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