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Mice, Inbred MRL lpr

Known as: Mouse, Inbred MRL lpr, Mice, MRL lpr, MRL lpr Mice 
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be… 
National Institutes of Health

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In BloodMicrobiologicalphysiological aspects

Papers overview

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2009
2009
Fluoride occurrence and assessment of exposure dose of fluoride in shallow aquifers of Makur, Unnao district Uttar Pradesh, India
The water samples from the shallow aquifers of Makur, Unnao district, Uttar Pradesh, was analyzed for fluoride content (F − ) and… 
Highly Cited
2000
Highly Cited
2000
In vivo disruption of the fas pathway abrogates gastric growth alterations secondary to Helicobacter infection.
Helicobacter infection is associated with gastric cell growth alterations, plausibly predisposing to ulcer disease and gastric… 
Highly Cited
1999
Highly Cited
1999
B7 costimulation in the development of lupus: autoimmunity arises either in the absence of B7.1/B7.2 or in the presence of anti-b7.1/B7.2 blocking antibodies.
Costimulatory molecules, termed B7.1 and B7.2, are present on the surfaces of APC and are important for the activation of T… 
1999
1999
The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the MRL-lpr mouse model.
OBJECTIVE Mice of the MRL-lpr strain develop a severe autoimmune arthritic condition when primed with complete Freund's adjuvant… 
Highly Cited
1996
Highly Cited
1996
Spontaneously produced anti‐DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells
Apoptosis has received increased attention over the past decade, and it is established as an essential process in physiological… 
1994
1994
Photodynamic therapy; a comparison with other immunomodulatory treatments of adjuvant‐enhanced arthritis in MRL‐lpr mice
Although numerous experimentat immunomodulalory regimens have been reported to be effective in the treatment of rheumatoid… 
1988
1988
Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel-14 in vivo.
MRL-lpr/lpr mice develop massive lymphadenopathy and autoimmunity. There is evidence that both migration and local proliferation… 
1988
1988
Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice.
MRL-lpr/lpr (lpr) mice spontaneously develop massive lymphadenopathy resulting from the expansion of a unique population of Thy-1… 
1987
1987
Isotype progression and clonality of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice.
Antibodies to the nuclear ribonucleoprotein Sm are found in 25% of MRL/Mp-lpr/lpr mice, which develop a syndrome similar to human… 
1983
1983
A monoclonal antibody (100C5) to the Lyt‐2− T cell population expanding in MRL/Mp‐lpr/lpr mice detects a surface antigen normally expressed on Lyt‐2+ cells and B cells
MRL/Mp‐lpr/lpr (MRL‐lpr) mice develop a generalized lymphadenopathy reflecting the expansion of a Lyt‐2− T cell population. The… 
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