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Methylmalonyl-CoA Mutase

Known as: Mutase, Methylmalonyl-CoA, Methylmalonyl CoA Mutase, Methylmalonyl-CoA Isomerase 
An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Methylmalonic and propionic acidemia (MMA/PA) are inborn errors of metabolism characterized by accumulation of propionic acid and… Expand
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Review
2012
Review
2012
Vitamin B12 is an organometallic compound with important metabolic derivatives that act as cofactors of certain enzymes, which… Expand
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Highly Cited
2010
Highly Cited
2010
Vitamin B(12) (cobalamin, Cbl) is essential to the function of two human enzymes, methionine synthase (MS) and methylmalonyl-CoA… Expand
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Highly Cited
2008
Highly Cited
2008
Mycobacterium tuberculosis is predicted to subsist on alternative carbon sources during persistence within the human host… Expand
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2006
2006
Methylmalonic acidopathy resulting from severe methylmalonyl-CoA mutase deficiency causes acute, potentially lethal ketoacidotic… Expand
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1998
1998
BACKGROUND Methylmalonyl CoA mutase catalyses the interconversion of succinyl CoA and methylmalonyl CoA via a free radical… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The enzyme methylmalonyl-coenzyme A (CoA) mutase, an alphabeta heterodimer of 150 kDa, is a member of a class of… Expand
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1994
1994
Methylmalonic acidemia resulting from genetic deficiency of methylmalonyl CoA mutase (MCM) is an often fatal metabolic disease… Expand
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Highly Cited
1993
Highly Cited
1993
A method is described by which the time-course of thrombin generation in plasma can be obtained from a continuous optical density… Expand
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1977
1977
The granulocyte R-type cobalamin binding protein delivers cobalamin (Cbl) exclusively to hepatocytes, and transcobalamin II… Expand
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