Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Methylenetetrahydrofolate Dehydrogenase (NADP+)

Known as: Dehydrogenase, Methylenetetrahydrofolate, Methylenetetrahydrofolate Dehydrogenase (NADP) [Chemical/Ingredient], Methylenetetrahydrofolate Dehydrogenase 
An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Controlling supplies for DNA and RNA synthesis The mTORC1 protein kinase complex regulates anabolic metabolism and coordinates… Expand
Is this relevant?
Highly Cited
2014
Highly Cited
2014
ATP is the dominant energy source in animals for mechanical and electrical work (for example, muscle contraction or neuronal… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Polymorphisms in folate pathway genes may influence the susceptibility to acute lymphoblastic leukemia (ALL). DNA was isolated… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The interconversion of folates by the one-carbon metabolism pathway is essential for the synthesis of precursors used in DNA… Expand
  • figure 1
  • table 1
  • table 2
  • table 4
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Background Folate metabolism pathway genes have been examined for association with neural tube defects (NTDs) because folic acid… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
We studied whether common polymorphisms in genes involved in folate metabolism affect methotrexate (MTX) sensitivity. Ex vivo MTX… Expand
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Purpose: We analyzed pretherapeutic gene expression patterns of patients with locally advanced adenocarcinomas of the esophagus… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
ABSTRACTThe central role of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methylenetetrahydrofolate dehydrogenase (MTHFD1… Expand
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Women who take folic acid periconceptionally reduce their risk of having a child with a neural tube defect (NTD) by >50%. A… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
To the Editor: Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5… Expand
Is this relevant?