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Methyl CpG Binding Domain

Known as: Methyl CpG DNA Binding Domain 
A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal… Expand
National Institutes of Health

Related topics

Related topics

4 relations
DNA MethylationMethyl-CpG-Binding Protein 2aspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex
Inhalants containing the volatile solvent toluene are misused to induce euphoria or intoxication. Inhalant abuse is most common… Expand
2018
2018
Genome-wide analysis of genes encoding MBD domain-containing proteins from tomato suggest their role in fruit development and abiotic stress responses
In tomato, DNA methylation has an inhibitory effect on fruit ripening. The inhibition of DNA methyltransferase by 5-azacytidine… Expand
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2016
2016
AtMBD6, a methyl CpG binding domain protein, maintains gene silencing in Arabidopsis by interacting with RNA binding proteins
ABSTRACTDNA methylation, mediated by double-stranded RNA, is a conserved epigenetic phenomenon that protects a genome from… Expand
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2016
2016
Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure*
The epigenetic information encoded in the genomic DNA methylation pattern is translated by methylcytosine binding proteins like… Expand
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Review
2015
Review
2015
[Structure basis of versatile base recognition of MBD4].
DNA methylation is one of the major epigenetic marks in the mammalian genome to define chromatin higher-order structure, and… Expand
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2015
2015
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells
DNA methylation is thought to induce transcriptional silencing through the combination of two mechanisms: the repulsion of… Expand
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2015
2015
Dynamics of MBD 2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells
DNA methylation is thought to induce transcriptional silencing through the combination of two mechanisms: the repulsion of… Expand
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Highly Cited
2003
Highly Cited
2003
Heterogeneity in residual function of MeCP2 carrying missense mutations in the methyl CpG binding domain
Rett syndrome is a neurodevelopmental disorder with severe mental retardation caused by mutations in the MECP2 gene. Mutations in… Expand
Highly Cited
2001
Highly Cited
2001
Mutation spectrum in patients with Rett syndrome in the German population: Evidence of hot spot regions
Mutations in the MECP2 (Methyl‐CpG‐binding protein) gene recently have been reported to cause Rett syndrome (RTT), an X‐linked… Expand
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