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Methotrexate-Actinomycin-Chlorambucil Regimen

Known as: MAC, MAC Regimen 
A regimen consisting of methotrexate, dactinomycin (Actinomycin-D) and chlorambucil, used for the treatment of good-prognosis metastatic gestational… Expand
National Institutes of Health

Papers overview

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2020
2020
Introduction Myeloablative conditioning (MAC) regimens decrease the risk of relapse in pediatric patients undergoing… Expand
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2017
2017
OBJECTIVE To compare the efficacy and safety of 3 different regimens, namely MAC, FLAG and CAG, as the re-induction chemotherapy… Expand
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2016
2016
Reduced-intensity conditioning (RIC) has been shown to have similar overall survival (OS) but higher relapse rates compared with… Expand
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2016
2016
Salvage regimens containing mitoxantrone have been successfully used for the treatment of primary induction failure or relapsed… Expand
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2015
2015
Refractory cytopenia of childhood (RCC) is the most common subtype of myelodysplastic syndrome in children, and the clinical… Expand
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2014
2014
Background: A recent prospective study (Socie & al Blood 2011) demonstrated that the addition of antithymocyte globulins (ATG) to… Expand
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2007
2007
BACKGROUND & OBJECTIVE Hematopoietic stem cell transplantation could improve the prognosis of malignant hematologic diseases… Expand
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Highly Cited
2006
Highly Cited
2006
We assessed the safety and efficacy of melphalan, arsenic trioxide (ATO) and ascorbic acid (AA) (MAC) combination therapy for… Expand
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1998
1998
A retrospective and comparative study of high‐risk gestational trophoblastic tumor (GTT) treated with different chemoregimen from… Expand
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1977
1977
A randomized trial of Adriamycin (A) in combination with melphalan (M), (MA therapy), and in combination with M plus… Expand
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