Metformin hydrochloride

Known as: 1,1-Dimethylbiguanide Hydrochloride, HCl, Metformin, Hydrochloride, Metformin 
The hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. Metformin inhibits complex I (NADPH… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
020406019802018

Papers overview

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Highly Cited
2013
Highly Cited
2013
IMPORTANCE Acute pancreatitis has significant morbidity and mortality. Previous studies have raised the possibility that… (More)
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2008
2008
The low bioavailability and short half-life of metformin hydrochloride (MH) make the development of sustained-release forms… (More)
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2008
2008
To the Editor: The antihyperglycaemic effect of metformin is generally attributed to a decrease in hepatic glucose output, with… (More)
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2008
2008
A simple, precise, rapid, and reproducible reversed-phase high-performance liquid chromatography method is developed for the… (More)
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2008
2008
A high performance reverse phase liquid chromatographic procedure is developed for simultaneous estimation of metformin… (More)
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2006
2006
In this study, metformin hydrochloride (MH) sustained-release pellets were successfully prepared by centrifugal granulation. Seed… (More)
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2004
2004
BACKGROUND In 2002, fixed-dose combination therapy (FDCT) with rosiglitazone maleate plus metformin hydrochloride became… (More)
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2004
2004
A rapid and sensitive liquid chromatography-tandem mass spectrometric (LC-MS-MS) method for the determination of metformin in… (More)
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2003
2003
An 18 year-old-woman presented with a 1-week history of a psoriasiform eruption on her limbs and trunk that began 1 week after… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Most antidiabetic agents target only 1 of several underlying causes of diabetes. The complementary actions of the… (More)
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