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Meldrum's acid

Known as: 2,2-dimethyl-1,3-dioxane-4,6-dione, cyclic isopropylidene malonate 
 
National Institutes of Health

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1 relation

Broader (1)

Dioxanes

Papers overview

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2018
2018
Reactions of N-Heterocyclic Carbene Boranes with 5-Diazo-2,2-dimethyl-1,3-dioxane-4,6-dione: Synthesis of Mono- and Bis-hydrazonyl NHC-Boranes.
N-Heterocyclic carbene boranes (NHC-boranes) react with 5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dione at 40 °C in dichloromethane to… Expand
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2014
2014
Design and synthesis of pyrido[2,1-b][1,3,5]thiadiazine library via uncatalyzed Mannich-type reaction.
This Research Article describes the synthesis of an over 700-member library of (8R/8S)-3-R-8-aryl-6-oxo-3,4,7,8-tetrahydro-2H,6H… Expand
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2014
2014
Di- and triarylmethylium ions as probes for the ambident reactivities of carbanions derived from 5-benzylated Meldrum's acid.
The kinetics of the reactions of carbocations with carbanions 1 derived from 5-benzyl-substituted Meldrum's acids 1-H (Meldrum's… Expand
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2014
2014
Ultrasound-assisted sequential multicomponent strategy for the combinatorial synthesis of novel coumarin hybrids.
The present investigation reports an easy access to a library of novel spiro-oxindole-pyrrolizine or pyrrolo[1,2-c]thiazole fused… Expand
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2010
2010
Meldrum's acids and 5-alkylidene Meldrum's acids in catalytic carbon-carbon bond-forming processes.
Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) is a molecule with a unique history, owing to its originally misassigned… Expand
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2007
2007
Ab initio structure determination of 5-anilinomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione from laboratory powder data--a combined use of X-ray, molecular and solid-state DFT study.
The crystal structure of the title compound was solved from laboratory powder diffraction data in the triclinic group P\bar 1 by… Expand
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2006
2006
Inhibition of photosystem II electron transport by acyl derivatives of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's acid).
In the course of the synthesis of gamma-pyrones, well-known inhibitors of photosystem II electron transport, it turned out that… Expand
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2005
2005
p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
BACKGROUND Understanding the myocardial inflammatory response to ischemia is an important part of achieving the elusive clinical… Expand
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2004
2004
Highly regio- and chemoselective palladium-catalyzed propargylallylation of activated olefins: a novel route to 1,7-enyne derivatives.
An efficient method for the synthesis of 1,7-enyne derivatives via phosphine-palladium-catalyzed three-component assembling of… Expand
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2003
2003
Antiepileptic Drugs. 2002. Fifth Edition. Edited by Rene Levy, Richard Mattson, Brian Meldrum, Emilio Perucca. Published by Lippincott, Williams and Wilkins. 968 pages. C$285 approx.
 
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