Melanotropin Alpha, human

Known as: Alpha-MSH, ACTH(1-13), ACTH (1-13) 
Melanotropin alpha (13 aa, ~2 kDa) is encoded by the human POMC gene. This protein is involved in the positive regulation of melanin production.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Protein tyrosine phosphatase 1B (PTP1B) and SH2 domain-containing protein tyrosine phosphatase-2 (SHP2) have been shown in mice… (More)
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Highly Cited
2009
Highly Cited
2009
Melanin-based traits involved in animal communication have been traditionally viewed as occurring under strict genetic control… (More)
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2009
2009
Exposure of cultured human melanocytes to ultraviolet radiation (UV) results in DNA damage. In melanoma, UV-signature mutations… (More)
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2007
2007
The alpha-melanocyte-stimulating hormone (alpha-MSH) receptor (melanocortin type 1 receptor, or MC1R) plays an important role in… (More)
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Highly Cited
2005
Highly Cited
2005
UV radiation is an important etiologic factor for skin cancer, including melanoma. Constitutive pigmentation and the ability to… (More)
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Review
2004
Review
2004
The importance of the central melanocortin system in the regulation of energy balance is highlighted by studies in transgenic… (More)
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Review
2003
Review
2003
The characterization of the melanocortin 1 receptor (MC1R) expressed on human melanocytes and the findings that certain mutations… (More)
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2000
2000
The mediobasal hypothalamus regulates functions necessary for survival, including body energy balance and adaptation to stress… (More)
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Highly Cited
1999
Highly Cited
1999
The melanocortin 1 receptor is a G-protein-coupled receptor that acts as a control point for control of the eumelanin… (More)
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1998
1998
A hallmark of sun exposure is increased melanin synthesis by cutaneous melanocytes which protects against photodamage and… (More)
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