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Melanocortin 3 Receptor

Known as: Receptor, Melanocortin 3, Melanocortin-3 Receptor, Receptor, MC3 
A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH; GAMMA-MSH and ADRENOCORTICOTROPIC HORMONE.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Functionally significant heterozygous mutations in the Melanocortin-4 receptor (MC4R) have been implicated in 2.5% of early onset… Expand
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Review
2008
Review
2008
The adipose tissue-derived hormone leptin acts via its receptor (LRb) in the brain to regulate energy balance and neuroendocrine… Expand
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Highly Cited
2008
Highly Cited
2008
Entrainment of anticipatory activity and wakefulness to nutrient availability is a poorly understood component of energy… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Melanocortin 3 receptor (MC3R) plays a critical role in weight regulation of rodents, but its role in humans remains… Expand
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Highly Cited
2002
Highly Cited
2002
Agouti-related protein (AgRP), a neuropeptide abundantly expressed in the arcuate nucleus of the hypothalamus, potently… Expand
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Review
2001
Review
2001
Arcuate nucleus neurons are known to be responsive to a wide array of hormones and nutrients, including leptin, insulin, gonadal… Expand
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Highly Cited
2000
Highly Cited
2000
Genetic and pharmacological studies have defined a role for the melanocortin-4 receptor (Mc4r) in the regulation of energy… Expand
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Highly Cited
2000
Highly Cited
2000
The central melanocortin system is critical for the long term regulation of energy homeostasis. Null mutations of the… Expand
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Highly Cited
2000
Highly Cited
2000
Melanocortin-4 receptor (Mc4r)-null mice exhibit late-onset obesity. To determine whether aberrant metabolism contributes to the… Expand
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Highly Cited
2000
Highly Cited
2000
Studies using nonselective agonists and antagonists of melanocortin-3 receptor (MC3R) and MC4R point to the importance of the CNS… Expand
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