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Megakaryocytopoiesis

Known as: Megakaryocytopoieses, Megakaryopoiesis 
A complex process that involves the proliferation of MEGAKARYOCYTES in BONE MARROW, their differentiation in size and ploidy, and maturation before… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
microRNAs are a highly conserved class of noncoding RNAs with important regulatory functions in proliferation, apoptosis… Expand
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Highly Cited
2003
Highly Cited
2003
To determine if megakaryocytes are targeted by immune thrombocytopenic purpura (ITP) autoantibodies, as are platelets, we have… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE 5-Aza-2'-deoxycytidine (decitabine; DAC) is a DNA hypomethylating agent that has shown a 50% response rate in a small… Expand
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Highly Cited
1999
Highly Cited
1999
Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML, MIM 601399) is an autosomal dominant… Expand
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Highly Cited
1996
Highly Cited
1996
Mice with a null mutation in the thrombopoietin (TPO) receptor c-Mpl were generated by gene targeting. c-mpl-deficient mice… Expand
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Highly Cited
1996
Highly Cited
1996
Thrombopoietin (TPO) has recently been cloned and shown to regulate megakaryocyte and platelet production by activating the… Expand
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Highly Cited
1995
Highly Cited
1995
Thrombopoietin (Tpo), the ligand for the c-mpl receptor, is a major regulator of platelet production in vivo. Treatment of mice… Expand
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Highly Cited
1994
Highly Cited
1994
Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and thrombopoietin, which respectively… Expand
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Highly Cited
1994
Highly Cited
1994
MEGAKARYOCYTOPOIESIS is the cellular developmental process that leads to platelet production. At least two humoral growth factors… Expand
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Highly Cited
1993
Highly Cited
1993
The proto-oncogene c-mpl encodes a protein whose sequence shares striking homologies with members of the highly conserved… Expand
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