Megakaryocytopoiesis

Known as: Megakaryocytopoieses, Megakaryopoiesis 
A complex process that involves the proliferation of MEGAKARYOCYTES in BONE MARROW, their differentiation in size and ploidy, and maturation before… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
microRNAs are a highly conserved class of noncoding RNAs with important regulatory functions in proliferation, apoptosis… (More)
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Highly Cited
2004
Highly Cited
2004
Thrombopoietin (Tpo) is the primary cytokine regulating megakaryocyte development and platelet production. Tpo signaling through… (More)
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Highly Cited
2003
Highly Cited
2003
To determine if megakaryocytes are targeted by immune thrombocytopenic purpura (ITP) autoantibodies, as are platelets, we have… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE For approximately 5% of autologous transplant recipients and a higher proportion of allogeneic transplant recipients… (More)
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Highly Cited
1999
Highly Cited
1999
Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML, MIM 601399) is an autosomal dominant… (More)
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Highly Cited
1996
Highly Cited
1996
Thrombopoietin (TPO) has recently been cloned and shown to regulate megakaryocyte and platelet production by activating the… (More)
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Highly Cited
1996
Highly Cited
1996
Mice with a null mutation in the thrombopoietin (TPO) receptor c-Mpl were generated by gene targeting. c-mpl-deficient mice… (More)
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Highly Cited
1994
Highly Cited
1994
Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and thrombopoietin, which respectively… (More)
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Highly Cited
1994
Highly Cited
1994
MEGAKARYOCYTOPOIESIS is the cellular developmental process that leads to platelet production. At least two humoral growth factors… (More)
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Review
1989
Review
1989
http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in… (More)
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