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Meclizine

Known as: Meclizine [Chemical/Ingredient], Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)-, Parachloramine 
A synthetic piperazine with anti-emetic, sedative and histamine H1antagonistic properties. Meclizine blocks the H1 histamine receptor and prevents… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Seasonal changes in the concentration of 21 pharmaceuticals in a wastewater treatment plant (WWTP) in České Budějovice were… Expand
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Highly Cited
2012
Highly Cited
2012
A multi-residue method for the simultaneous determination of more than 90 pharmaceuticals in water samples was developed and… Expand
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Highly Cited
2012
Highly Cited
2012
SummaryThe antimotion sickness drugs protect a high percentage of individuals from becoming motion sick if the proper drug is… Expand
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2011
2011
Defects in cellular energy metabolism represent an early feature in a variety of human neurodegenerative diseases. Recent studies… Expand
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Review
2006
Review
2006
Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are members of the nuclear receptor superfamily. These… Expand
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Highly Cited
2005
Highly Cited
2005
BackgroundMore than one-half of all pregnant women suffer from nausea and vomiting during pregnancy (NVP), primarily during the… Expand
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Highly Cited
2003
Highly Cited
2003
Background.  Nausea and vomiting in pregnancy (NVP) is a common complaint but risk factors for NVP are not well characterized. 
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Highly Cited
2001
Highly Cited
2001
Formalin injected subcutaneously into the paw is a widely used model of pain. This procedure evokes a short-lasting period of… Expand
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Highly Cited
2000
Highly Cited
2000
We assessed the effects of 78 potential chemopreventive agents in the F344 rat using two assays in which the inhibition of… Expand
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Highly Cited
1999
Highly Cited
1999
We combined in a previously derived three-dimensional model of the histamine H1 receptor (Ter Laak, A. M., Timmerman, H., Leurs… Expand
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