Mecamylamine

Known as: Bicyclo(2.2.1)heptan-2-amine, N,2,3,3-tetramethyl-, Mecamylamine [Chemical/Ingredient] 
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Attention exerts a strong influence over neuronal processing in cortical areas. It selectively increases firing rates and affects… (More)
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2005
2005
BACKGROUND Recent evidence suggests that some of the behavioral effects of alcohol may be mediated through actions on nicotinic… (More)
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Highly Cited
2005
Highly Cited
2005
Endothelial cell activation plays a critical role in regulating leukocyte recruitment during inflammation and infection. Based on… (More)
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Highly Cited
2001
Highly Cited
2001
Because mecamylamine, a nicotinic receptor antagonist, is used so often in nicotine research and because mecamylamine may have… (More)
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Highly Cited
1998
Highly Cited
1998
Mesolimbocortical dopamine (DA) neurotransmission is important in the mediation of the dependence-producing actions of nicotine… (More)
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Review
1998
Review
1998
 Nicotinic cholinergic systems are involved with several important aspects of cognitive function including attention, learning… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVE To evaluate concurrent administration of mecamylamine (nicotine antagonist) with nicotine skin patch treatment for… (More)
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Highly Cited
1994
Highly Cited
1994
Recently, a rodent model of nicotine abstinence syndrome has been developed based on observing the frequency of spontaneous… (More)
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Highly Cited
1993
Highly Cited
1993
It has been suggested that ethanol may interact with the central nicotinic acetylcholine receptor, thus providing a basis for the… (More)
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Highly Cited
1989
Highly Cited
1989
Intravenous nicotine maintained substantial responding on the drug-reinforced lever with a limited-access, fixed-ratio 5 schedule… (More)
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