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Mature T-Lymphocyte

Known as: Mature T-Cell 
A lymphocyte derived from a pre T-lymphocyte in the thymus and stored in secondary lymphoid organs, bone marrow, and lymph nodes. It circulates in… Expand
National Institutes of Health

Related topics

Related topics

20 relations
Anaplastic Large Cell Lymphoma, ALK-NegativeAnaplastic Large Cell Lymphoma, ALK-PositiveAnaplastic small cell lymphomaCentral Nervous System Anaplastic Large Cell Lymphoma
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Phase II study of the PD1-inhibitor pembrolizumab for the treatment of relapsed or refractory mature t-cell lymphoma.
7568Background: PDL-1 is often expressed on tumor cells or in the microenvironment of T-cell NHL (Wilcox RA. Blood 2009) making… Expand
2014
2014
Belinostat for Peripheral T-Cell Lymphoma
the peripheral t-cell lymphomas (ptCLs) are a diverse group of mature t-cell neoplasms that typically display aggressive clinical… Expand
2007
2007
Simultaneous diagnosis of CD3+ T-cell large granular lymphocyte leukaemia and true thymic hyperplasia.
CD3+ T-cell large granular lymphocyte (LGL) leukaemia is a mature T-cell neoplasm of cytotoxic T-lymphocytes. Neutropenia… Expand
Highly Cited
1999
Highly Cited
1999
Green fluorescent protein-transgenic mice: immune functions and their application to studies of lymphocyte development.
Green fluorescent protein (GFP) transgenic (GFP+) mice express GFP in most tissues except erythrocytes and hair. Immune responses… Expand
Review
1998
Review
1998
The role of interleukin-7 in early T-cell development.
Interleukin-7 (IL-7) is a non redundant cytokine in thymic T-cell development. It binds to a dimeric receptor consisting of a… Expand
Review
1996
Review
1996
Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes.
The precursor T-cell receptors (TCRs) and B-cell receptors (BCRs) direct lymphocyte development to the mature T-cell and B-cell… Expand
1993
1993
Evolution of a CD3+/CD+ α/ β T-Cell Receptor+ Mature T-Cell Clone from CD3-CD7+ Sorted Human Bone Marrow Cells
In order to study extrathymic differentiation in vitro, CD7+CD3- lymphocytes were sorted from normal human bone marrow and… Expand
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Highly Cited
1991
Highly Cited
1991
CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
A CONTINUOUS but low input of stem cells or 'prothymocytes' is necessary to maintain T-cell development in the adult thymus1, but… Expand
Highly Cited
1985
Highly Cited
1985
Identification of a Cell Surface Protein Complex Mediating Phorbol Ester‐Induced Adhesion (Binding) among Human Mononuclear Leukocytes
Phorbol esters rapidly induce aggregation of human mononuclear leukocytes in vitro. Previous studies have indicated that cell… Expand
1983
1983
Persistent in vitro infection by human T‐cell leukemia‐lymphoma virus (HTLV) of normal human T‐lymphocytes from blood relatives of patients with HTLV‐associated mature T‐cell neoplasms
Human T‐cell lymphoma‐leukemia virus (HTLV), a novel type‐C retrovirus, has been identified in tumor cells of patients with… Expand
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