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Mature T-Lymphocyte

Known as: Mature T-Cell 
A lymphocyte derived from a pre T-lymphocyte in the thymus and stored in secondary lymphoid organs, bone marrow, and lymph nodes. It circulates in… Expand
National Institutes of Health

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Anaplastic Large Cell Lymphoma, ALK-NegativeAnaplastic Large Cell Lymphoma, ALK-PositiveAnaplastic small cell lymphomaCentral Nervous System Anaplastic Large Cell Lymphoma
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Papers overview

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2018
2018
Phase II study of the PD1-inhibitor pembrolizumab for the treatment of relapsed or refractory mature t-cell lymphoma.
7568Background: PDL-1 is often expressed on tumor cells or in the microenvironment of T-cell NHL (Wilcox RA. Blood 2009) making… Expand
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2014
2014
Belinostat for Peripheral T-Cell Lymphoma
the peripheral t-cell lymphomas (ptCLs) are a diverse group of mature t-cell neoplasms that typically display aggressive clinical… Expand
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Review
2009
Review
2009
PSGL-1 function in immunity and steady state homeostasis.
The substantial importance of P-selectin glycoprotein ligand 1 (PSGL-1) in leukocyte trafficking has continued to emerge beyond… Expand
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1999
1999
Green fluorescent protein-transgenic mice: immune functions and their application to studies of lymphocyte development.
Green fluorescent protein (GFP) transgenic (GFP+) mice express GFP in most tissues except erythrocytes and hair. Immune responses… Expand
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Review
1998
Review
1998
The role of interleukin-7 in early T-cell development.
Interleukin-7 (IL-7) is a non redundant cytokine in thymic T-cell development. It binds to a dimeric receptor consisting of a… Expand
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Review
1996
Review
1996
Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes.
The precursor T-cell receptors (TCRs) and B-cell receptors (BCRs) direct lymphocyte development to the mature T-cell and B-cell… Expand
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1993
1993
Evolution of a CD3+/CD+ α/ β T-Cell Receptor+ Mature T-Cell Clone from CD3-CD7+ Sorted Human Bone Marrow Cells
In order to study extrathymic differentiation in vitro, CD7+CD3- lymphocytes were sorted from normal human bone marrow and… Expand
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Highly Cited
1991
Highly Cited
1991
CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
Abstract A CONTINUOUS but low input of stem cells or 'prothymocytes' is necessary to maintain T-cell development in the adult… Expand
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1985
1985
Identification of a cell surface protein complex mediating phorbol ester-induced adhesion (binding) among human mononuclear leukocytes.
Phorbol esters rapidly induce aggregation of human mononuclear leukocytes in vitro. Previous studies have indicated that cell… Expand
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1983
1983
Persistent in vitro infection by human T-cell leukemia-lymphoma virus (HTLV) of normal human T-lymphocytes from blood relatives of patients with HTLV-associated mature T-cell neoplasms.
Human T-cell lymphoma-leukemia virus (HTLV), a novel type-C retrovirus, has been identified in tumor cells of patients with… Expand
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