Skip to search formSkip to main contentSkip to account menu

Malignant neoplasm of central nervous system

Known as: Cancer of the Central Nervous System, Malignant Tumor of CNS, Malignant CNS Neoplasms 
A primary or metastatic malignant neoplasm involving the brain or spinal cord. Representative examples include anaplastic astrocytoma, glioblastoma… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

CNS disorderCentral Nervous System Neoplasms
Central Nervous SystemNeoplastic CellNervous system structureTurcot Syndrome Type 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Hybrid Gd3+/cisplatin cross-linked polymer nanoparticles enhance platinum accumulation and formation of DNA adducts in glioblastoma cell lines.
Glioblastoma is the most frequent and aggressive primary malignant tumor of the central nervous system with a gloomy prognosis… 
Review
2008
Review
2008
Small molecular inhibitors of p-STAT3: novel agents for treatment of primary and metastatic CNS cancers.
High-grade primary and metastatic central nervous system (CNS) tumors are common, deadly, and refractory to conventional therapy… 
2004
2004
Use of donors with central nervous system malignancies: Proceed with caution
2001
2001
Reconciling animal and human data in a cancer risk assessment of acrylonitrile.
OBJECTIVES Bioassays of rats exposed to acrylonitrile have consistently detected an elevated incidence of central nervous system… 
1998
1998
A new pineoblastoma cell line, PER-480, with der(10)t(10;17), der(16)t(1;16), and enhanced MYC expression in the absence of gene amplification.
1998
1998
Synthesis and anticancer evaluation of certain γ-aryloxymethyl-α-methylene-γ-phenyl-γ-butyrolactones
1996
1996
The potential of topoisomerase I inhibitors in the treatment of CNS malignancies: report of a synergistic effect between topotecan and radiation
SummaryDespite innovations in imaging, surgery, and radiation therapy, local failure remains the principle clinical problem in… 
1994
1994
Design and synthesis of ellipticinium salts and 1,2-dihydroellipticines with high selectivities against human CNS cancers in vitro.
9-Methoxy-2-methylellipticinium acetate (6), along with the 9-methyl and 9-chloro derivatives (7, and 8, respectively) have shown… 
1993
1993
In vitro cytotoxicity of GC sequence directed alkylating agents related to distamycin.
Imidazole containing analogues 7, 10, and 17 of distamycin wherein the C-terminus contain a dimethylamino moiety have been shown… 
1990
1990
Phase II study of homoharringtonine in patients with recurrent primary malignant central nervous system tumors
A phase 11 trial of Homoharringtonine (HHT) was performed in 15 patients with recurrent or progressive malignant glioma. The drug… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)