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Gastrinomas, a rare group of neuroendocrine tumors, are responsible for severe peptic disease and diarrhea. Although symptomatic… Expand Gastrinomas may occur in the pancreas, duodenum or peripancreatic lymph nodes. The gastrin overproduction leads to the Zollinger… Expand Ectopic Cushing's syndrome due to various malignancies is not uncommon. However, a few cases of ectopic Cushing's syndrome caused… Expand Malignant pancreatic endocrine tumors (PETs) have a poor prognosis and existing antitumor treatments are unsatisfactory. Recent… Expand Fifteen patients with Zollinger-EIlison syndrome followed at the National Institutes of Health with extensive metastatic disease… Expand Six patients (4 women, 2 men) with malignant gastrinoma developed multiple bone metastases; osteolytic as well as osteoblastic… Expand The advent of the histamine H2-receptor antagonists and the renewed interest in curative surgery in patients with gastrinoma have… Expand The effects of recent diagnostic and therapeutic advances were assessed in 65 patients with the Zollinger-Ellison syndrome (ZES… Expand The treatment with streptozotocin of a patient with metastatic gastrinoma is described. Two courses of intravenous streptozotocin… Expand Half of all patients with the Zollinger-Ellison syndrome treated by total gastrectomy will eventually die from their tumor. The… Expand