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Malignant Conversion

The transformation of a cell or cell population from a pre- or non-malignant condition to a malignant condition. (NCI)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Hepatocarcinogenesis is a multistage process in which precursor lesions progress into early hepatocellular carcinomas (eHCC) by… Expand
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2004
2004
The multistage evolution of squamous skin tumors induced by chemical or viral carcinogens on mice from different genetic… Expand
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Highly Cited
2003
Highly Cited
2003
Transforming growth factor beta (TGF-beta) is a growth-inhibitory cytokine for epithelial cells. In the mouse multistage skin… Expand
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Review
1999
Review
1999
Papillomaviruses cause certain common human cancers, most notably carcinoma of the cervix. The viral oncoproteins E6 and E7 are… Expand
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1998
1998
Ornithine decarboxylase (ODC) is aberrantly regulated in tumor cells and results in high basal levels of ODC and polyamines in… Expand
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Highly Cited
1993
Highly Cited
1993
Mouse skin carcinomas arise from a small subpopulation of benign papillomas with an increased risk of malignant conversion. These… Expand
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1992
1992
HUMAN papillomaviruses associated with cutaneous1 and ano-genital2 cancers induce intraepithelial precursor lesions which may… Expand
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Highly Cited
1983
Highly Cited
1983
Multi-stage carcinogenesis (initiation–promotion) was first demonstrated in mouse skin1,2. The first stage, initiation, is… Expand
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Highly Cited
1979
Highly Cited
1979
Abstract Fourteen patients with epidermodysplasia verruciformis were studied to correlate the type of human papillomavirus (HPV… Expand
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1973
1973
Summary Epithelial-like cells from rat liver were exposed in cell culture to aflatoxin B 1 , dimethylnitrosamine, N… Expand
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