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MYD88 gene

Known as: MYD88, Myeloid Differentiation Primary Response 88 Gene, myeloid differentiation primary response 88 
This gene is involved in the modulation of proinflammatory gene expression.
National Institutes of Health

Related topics

Related topics

6 relations
ImmunityMYD88 Gene MutationMyeloid Differentiation Primary Response Protein Myd88Signal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Estrogen promotes the metastasis of non‑small cell lung cancer via estrogen receptor β by upregulation of Toll‑like receptor 4 and activation of the myd88/NF‑κB/MMP2 pathway.
Estrogen promotes non‑small cell lung cancer (NSCLC) metastasis via estrogen receptor β (ERβ)‑mediated invasiveness‑associated… 
2019
2019
Identification, characterisation and preliminary functional analysis of IRAK-M in grass carp (Ctenopharyngodon idella).
2018
2018
MYD88 L265P mutation promoted malignant B cell resistance against T cell‐mediated cytotoxicity via upregulating the IL‐10/STAT3 cascade
2017
2017
Mapping the human T cell repertoire to recurrent driver mutations in MYD88 and EZH2 in lymphoma
ABSTRACT Oncogenic “driver” mutations are theoretically attractive targets for the immunotherapy of lymphoid cancers, yet the… 
2015
2015
MyD88-mediated TLR signaling protects against acute rotavirus infection while inflammasome cytokines direct Ab response
Rotavirus (RV) infects small intestinal epithelial cells, inducing severe diarrhea in children, resulting in over 500,000 deaths… 
2015
2015
Contributions of Unique Intracellular Domains to Switchlike Biosensing by Toll-like Receptor 4*
Background: TLR4 is an important receptor, promoting both protective immunity and inflammatory diseases. Results: A revised model… 
2014
2014
The TIR-domain-containing adapter inducing interferon-β-dependent signaling cascade plays a crucial role in ischemia–reperfusion-induced retinal injury, whereas the contribution of the myeloid…
Toll‐like receptor 4 (Tlr4) plays an important role in ischemia–reperfusion (IR)‐induced retinal inflammation and damage. However… 
Highly Cited
2008
Highly Cited
2008
Deletion of MyD88 markedly attenuates sepsis‐induced T and B lymphocyte apoptosis but worsens survival
Sepsis induces widespread lymphocyte apoptosis, resulting in impaired immune defenses and increased morbidity and mortality… 
Highly Cited
2008
Highly Cited
2008
Role for MyD88 Signaling in Murine Gammaherpesvirus 68 Latency
ABSTRACT Toll-like receptors (TLRs) are known predominantly for their role in activating the innate immune response. Recently… 
Review
2004
Review
2004
[TIR domain--containing adaptors regulate TLR-mediated signaling pathways].
Recognition of pathogens by Toll-like receptors (TLRs) triggers innate immune responses via signaling pathways mediated by… 
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