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MTF1 gene

Known as: METAL-REGULATORY TRANSCRIPTION FACTOR 1, MTF1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2014
01219942014

Papers overview

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2015
2015
Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc.
BACKGROUND Metallothionein (MT) proteins play critical roles in the physiological handling of both essential (Cu and Zn) and… (More)
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2013
2013
Prenatal zinc deficiency-dependent epigenetic alterations of mouse metallothionein-2 gene.
Zinc (Zn) deficiency in utero has been shown to cause a variety of disease states in children in developing countries, which… (More)
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2012
2012
Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1.
Mtf1 has been characterized as a mitochondrial transcription factor and is shown to regulat mitochondrial transcription. Mtf1 has… (More)
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2011
2011
A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1
In eukaryotic cells, Mtf1 and its homologues function as mitochondrial transcription factors for the mitochondrial RNA polymerase… (More)
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2010
2010
Mitochondrial transcription factor Mtf1 traps the unwound non-template strand to facilitate open complex formation.
The catalytic subunit of the mitochondrial (mt) RNA polymerase (RNAP) is highly homologous to the bacteriophage T7/T3 RNAP… (More)
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2009
2009
Induction of metallothionein I by arsenic via metal-activated transcription factor 1: critical role of C-terminal cysteine residues in arsenic sensing.
Metal-activated transcription factor 1 (MTF1) mediates the induction of metallothioneins I and II by zinc and stress signals. The… (More)
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2004
2004
Intrinsic promoter recognition by a "core" RNA polymerase.
Two classes of RNA polymerases transcribe RNA from promoters on DNA templates: promoter recognition-competent single polypeptides… (More)
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2002
2002
Retrovirally expressed metal response element-binding transcription factor-1 normalizes metallothionein-1 gene expression and protects cells against zinc, but not cadmium, toxicity.
Metal response element (MRE) transcription factor-1 (MTF1), a member of the Cys2-His2 class of zinc-finger transcription factors… (More)
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1998
1998
Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid.
Metallothioneins (MT) have been implicated in the protection of cells from oxidative stress. We studied the molecular mechanism… (More)
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1995
1995
Import of transcription factor MTF1 into the yeast mitochondria takes place through an unusual pathway.
We report studies of the import into mitochondria of MTF1, a nucleus-encoded factor that markedly stimulates the specific… (More)
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