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MTF1 gene

Known as: METAL-REGULATORY TRANSCRIPTION FACTOR 1, MTF1 
 
National Institutes of Health

Papers overview

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2020
2020
The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an auto-inhibitory mechanism that regulates DNA binding.
The structurally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of the mitochondrial RNA… Expand
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2012
2012
Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1.
Mtf1 has been characterized as a mitochondrial transcription factor and is shown to regulat mitochondrial transcription. Mtf1 has… Expand
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2011
2011
Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase.
Promoter recognition is the first and the most important step during gene expression. Our studies of the yeast (Saccharomyces… Expand
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2011
2011
A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1
In eukaryotic cells, Mtf1 and its homologues function as mitochondrial transcription factors for the mitochondrial RNA polymerase… Expand
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2011
2011
Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe
We have characterized the mitochondrial transcription factor (Mtf1) and RNA polymerase (Rpo41) of Schizosaccharomyces pombe… Expand
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2011
2011
The N-terminal domain of the yeast mitochondrial RNA polymerase regulates multiple steps of transcription.
Transcription of the yeast (Saccharomyces cerevisiae) mitochondrial (mt) genome is catalyzed by nuclear-encoded proteins that… Expand
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2010
2010
Mitochondrial transcription factor Mtf1 traps the unwound non-template strand to facilitate open complex formation.
The catalytic subunit of the mitochondrial (mt) RNA polymerase (RNAP) is highly homologous to the bacteriophage T7/T3 RNAP… Expand
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2009
2009
Fluorescence mapping of the open complex of yeast mitochondrial RNA polymerase.
The mitochondrial RNA polymerase (mtRNAP) of Saccharomyces cerevisiae, consisting of a complex of Rpo41 and Mtf1, is homologous… Expand
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2004
2004
Intrinsic promoter recognition by a "core" RNA polymerase.
Two classes of RNA polymerases transcribe RNA from promoters on DNA templates: promoter recognition-competent single polypeptides… Expand
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2004
2004
A mutation in the yeast mitochondrial core RNA polymerase, Rpo41, confers defects in both specificity factor interaction and promoter utilization.
The yeast mitochondrial RNA polymerase (RNAP) is composed of the core RNAP, Rpo41, and the mitochondrial transcription factor… Expand
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