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MT 141

Known as: MT-141 
National Institutes of Health

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cefminox

Papers overview

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1985
1985
The bacteriolytic action of MT-141, a new cephamycin antibiotic, on gram-negative bacteria.
MT-141, a new cephamycin (7 alpha-methoxy-cephalosporin) antibiotic with a D-cysteine moiety in its 7 beta-side chain, has… 
1985
1985
In-vitro and in-vivo activities of a novel cephamycin MT-141 against the Bacteroides fragilis group in comparison with six cephem antibiotics.
MT-141 inhibited 90% of the clinical isolates of Bacteroides fragilis at 3.13 mg/l, whereas six reference cephem antibiotics… 
1985
1985
Comparative bactericidal and morphological effects of five cephamycins on cells of three gram-negative bacilli at decreasing drug concentrations.
The bactericidal and morphological effects under drug-decreasing conditions of cefminox (MT-141), cefoxitin, cefmetazole… 
1984
1984
[Toxicological studies on a new cephamycin, MT-141 IX. Its teratogenicity test in rats and rabbits].
A teratogenicity study of MT-141 was performed in SD rats and Japanese white rabbits. The pregnant rats were administered… 
1984
1984
[Toxicological studies of a new cephamycin, MT-141. II. Its subacute toxicity in rats].
In this subacute study, male and female rats were administered with 100, 200, 400, 800 and 1,600 mg/kg/day of MT-141 through an… 
1984
1984
Therapeutic efficacy of a new cephamycin, MT-141, in compromised mice.
The antibacterial activity of MT-141 against Escherichia coli and Proteus morganii in compromised mice was investigated and… 
1984
1984
[Toxicological studies on a new cephamycin, MT-141. VIII. Its fertility test in rats].
A fertility study of MT-141 was performed in SD rats with the intramuscular (i.m.) injections at the dose levels of 400, 800 and… 
1984
1984
[Pharmacological studies on new cephamycin, MT-141. (1) Its effect on central nervous system, respiration and cardiovascular system].
The results on pharmacological effects of MT-141 were as follows. MT-141 did not exert effect on central nervous system in mice… 
1984
1984
In vivo antibacterial activity of a novel cephamycin, MT-141, on gram-negative infections in mice
1983
1983
Synthesis and biological activity of 7 beta-(2-amino-2-carboxy)-ethylthioacetamido-7 alpha-methoxycephalosporin derivatives.
C-7 and C-3 substituents of a new antibiotic SF-1623 were chemically modified to improve the bioactivity, and substituent effect…