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MSH4 protein, human
Known as:
MutS Protein Homolog 4
, MutS Homolog 4
, hMSH4
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MutS protein homolog 4 (936 aa, ~105 kDa) is encoded by the human MSH4 gene. This protein plays a role in reciprocal recombination and proper…
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (1)
Cell Cycle Proteins
Cell Nucleus
DNA Repair
DNA Repair Gene
DNA repair protein
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Formation of hMSH4-hMSH5 heterocomplex is a prerequisite for subsequent GPS2 recruitment.
Tai-Hsien Lee
,
W. Yi
,
M. Griswold
,
F. Zhu
,
C. Her
DNA repair
2006
Corpus ID: 8549968
Increasing evidence suggests that components of the DNA mismatch repair (MMR) pathway play multifunctional roles beyond the scope…
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Highly Cited
2004
Highly Cited
2004
Association between MSH4 (MutS homologue 4) and the DNA strand-exchange RAD51 and DMC1 proteins during mammalian meiosis.
S. Neyton
,
F. Lespinasse
,
+4 authors
S. Santucci-Darmanin
Molecular human reproduction
2004
Corpus ID: 16244485
During meiotic prophase, chromosomes must undergo highly regulated recombination events, some of which lead to reciprocal…
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2003
2003
Human MutS homologue MSH4 physically interacts with von Hippel-Lindau tumor suppressor-binding protein 1.
C. Her
,
Xiling Wu
,
M. Griswold
,
F. Zhou
Cancer research
2003
Corpus ID: 16386593
Increasing evidence indicated that the protein factors involved in DNA mismatch repair (MMR) possess meiotic functions beyond the…
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Highly Cited
2002
Highly Cited
2002
The DNA mismatch-repair MLH3 protein interacts with MSH4 in meiotic cells, supporting a role for this MutL homolog in mammalian meiotic recombination.
S. Santucci-Darmanin
,
S. Neyton
,
F. Lespinasse
,
A. Saunières
,
P. Gaudray
,
V. Paquis-Flucklinger
Human molecular genetics
2002
Corpus ID: 18621123
The mismatch-repair (MMR) system plays a central role in maintaining genetic stability and requires evolutionarily conserved…
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Highly Cited
2000
Highly Cited
2000
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
B. Kneitz
,
P. Cohen
,
+7 authors
W. Edelmann
Genes & development
2000
Corpus ID: 20901722
Msh4 (MutS homolog 4) is a member of the mammalian mismatch repair gene family whose members are involved in postreplicative DNA…
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Highly Cited
2000
Highly Cited
2000
MSH4 acts in conjunction with MLH1 during mammalian meiosis
S. Santucci-Darmanin
,
D. Walpita
,
F. Lespinasse
,
C. Desnuelle
,
T. Ashley
,
V. Paquis-Flucklinger
FASEB journal : official publication of the…
2000
Corpus ID: 10086536
MSH4 is a meiosis‐specific MutS homolog. In yeast, it is required for reciprocal recombination and proper segregation of…
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Highly Cited
1999
Highly Cited
1999
hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis.
T. Bocker
,
A. Barusevicius
,
+9 authors
R. Fishel
Cancer research
1999
Corpus ID: 3566702
MutS homologues have been identified in nearly all organisms examined to date. They play essential roles in maintaining mitotic…
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Highly Cited
1997
Highly Cited
1997
Cloning and expression analysis of a meiosis-specific MutS homolog: the human MSH4 gene.
V. Paquis-Flucklinger
,
S. Santucci-Darmanin
,
R. Paul
,
A. Saunières
,
C. Turc‐Carel
,
C. Desnuelle
Genomics
1997
Corpus ID: 9418643
The Escherichia coli MutHLS system has been highly conserved throughout evolution. The eukaryotic pathway results in a…
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Highly Cited
1994
Highly Cited
1994
Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction
P. Ross-Macdonald
,
G. Roeder
Cell
1994
Corpus ID: 28539509
MSH4 is a novel meiosis-specific gene required for wild-type levels of spore viability in S. cerevisiae. The predicted product of…
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Highly Cited
1989
Highly Cited
1989
Alpha-melanotropin: the minimal active sequence in the lizard skin bioassay.
A. L. Castrucci
,
M. E. Hadley
,
+7 authors
J. P. Riehm
General and comparative endocrinology
1989
Corpus ID: 36452132
alpha-Melanotropin (alpha-melanocyte-stimulating hormone, alpha-MSH) is a tridecapeptide, Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp…
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