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MR 2266

Known as: MR-2266 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

BenzomorphansNarcotic Antagonists

Narrower (2)

MR-2266-BSMr 2267

Papers overview

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1994
1994
Kappa-selective agonists decrease postsynaptic potentials and calcium components of action potentials in the supraoptic nucleus of rat hypothalamus in vitro
To investigate the effects of the endogenous kappa-receptor agonists dynorphin and leumorphin on neurons of the supraoptic… Expand
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1992
1992
kappa-Opioid receptor stimulation increases intracellular free calcium in isolated rat ventricular myocytes.
The effect of two specific kappa-agonists, dynorphinA1-13 and U50,488H, on intracellular free calcium [Ca]i in isolated rat… Expand
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1990
1990
Effects of the benzomorphan kappa-opiate, MR 2266 and its (+) enantiomer MR 2267, on thermonociceptive reactions in different strains of mice.
The effects of the benzomorphan kappa opiate MR 2266 and its dextro enantiomer MR 2267 were assessed on thermonociception in… Expand
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1989
1989
Role of central opiate receptor subtypes in the circulatory responses of awake rabbits to graded caval occlusions.
1. In unanaesthetized rabbits, haemorrhage was simulated by inflating a cuff placed round the inferior vena cava so that cardiac… Expand
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1989
1989
Modulation of appetitively and aversively motivated behavior by the kappa opioid antagonist MR2266.
MR2266 (MR), an opioid antagonist that binds to kappa and mu receptors, was examined for its ability to influence the aversively… Expand
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1988
1988
Influence of narcotic antagonist drugs upon nitrous oxide analgesia in mice
Nitrous oxide produced a concentration-related suppression of phenylquinone-induced abdominal constriction in mice. This… Expand
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1985
1985
Spinal cord dynorphin may modulate nociception via a ℵ-opioid receptor in chronic arthritic rats
Abstract Inoculation of rats with Mycobacterium butyricum produced an arthritis of the limbs which revealed an enhanced… Expand
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Highly Cited
1983
Highly Cited
1983
U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.
U-50,488 (trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide) displays analgesic actions in a variety… Expand
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1982
1982
U-50,488, a selective kappa opioid agonist: Comparison to other reputed kappa agonists
1. U-50,488 is a structurally novel, non-mu opioid. In the present experiments it was compared to the reputed kappa opioid… Expand
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1978
1978
Enhancement of a nociceptive reaction by opioid antagonists in mice.
1. The opioid antagonists, naloxone, GPA 2163, levallorphan and Mr-2266 reduced the latency of the jumping reaction of mice in… Expand
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