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MR 2266

Known as: MR-2266 
National Institutes of Health

Papers overview

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1999
1999
Mr 2266 [(-)-(1R,5R,9R)-5,9-diethyl-2-(3-furylmethyl)-2’-hydroxy-6,7-benzomorphan] is an antagonist at κ-opioid receptors and at… Expand
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1994
1994
To investigate the effects of the endogenous kappa-receptor agonists dynorphin and leumorphin on neurons of the supraoptic… Expand
1991
1991
The effect of U-50,488H, a selective kappa-receptor agonist, on memory functions in an animal model of cerebral ischemia was… Expand
Highly Cited
1989
Highly Cited
1989
1. In unanaesthetized rabbits, haemorrhage was simulated by inflating a cuff placed round the inferior vena cava so that cardiac… Expand
Highly Cited
1988
Highly Cited
1988
Nitrous oxide produced a concentration-related suppression of phenylquinone-induced abdominal constriction in mice. This… Expand
Highly Cited
1985
Highly Cited
1985
Abstract Inoculation of rats with Mycobacterium butyricum produced an arthritis of the limbs which revealed an enhanced… Expand
Highly Cited
1983
Highly Cited
1983
U-50,488 (trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide) displays analgesic actions in a variety… Expand
Highly Cited
1982
Highly Cited
1982
1. U-50,488 is a structurally novel, non-mu opioid. In the present experiments it was compared to the reputed kappa opioid… Expand
Highly Cited
1982
Highly Cited
1982
Posterior pituitaries of obese mice (ob/ob) contained significantly more immunoreactive dynorphin (P less than .01) and leu… Expand
Highly Cited
1978
Highly Cited
1978
1 The opioid antagonists, naloxone, GPA 2163, levallorphan and Mr‐2266 reduced the latency of the jumping reaction of mice in the… Expand