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MORC Family CW-Type Zinc Finger Protein 3, human

Known as: Zinc Finger CW-Type Coiled-Coil Domain Protein 3, MORC Family CW-Type Zinc Finger Protein 3, Nuclear Matrix Protein 2 
MORC family CW-type zinc finger protein 3 (939 aa, ~107 kDa) is encoded by the human MORC3 gene. This protein is involved in both RNA binding and… Expand
National Institutes of Health

Related topics

Related topics

7 relations
Cell AgingLigand BindingMORC3 geneMetal Binding Site
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Papers overview

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2019
2019
SAT0655 THE SPECTRUM OF MYOSITIS ANTIBODIES: CLINICAL CORRELATION AND PREVALENCE OF ANTI-DFS70
Background: Myositis can be a clinical feature of several rheumatic diseases. In inflammatory idiopathic myopathies (IIM), such… Expand
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2017
2017
NXP-2 Positive Dermatomyositis: A Unique Clinical Presentation
Dermatomyositis (DM), a myopathy associated with inflammation and muscle weakness, has historically been difficult to diagnose… Expand
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Review
2017
Review
2017
Cutaneous and Systemic Findings Associated With Nuclear Matrix Protein 2 Antibodies in Adult Dermatomyositis Patients.
OBJECTIVE To characterize the cutaneous and systemic clinical phenotype of dermatomyositis patients with antinuclear matrix… Expand
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2016
2016
Calcinosis in poly-dermatomyositis: clinical and laboratory predictors and treatment options.
OBJECTIVES We aimed to identify the possible clinical and laboratory predictors of calcinosis in a cohort of patients with a… Expand
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2015
2015
Autoantikörper bei juveniler idiopathischer inflammatorischer Myopathie
Klassische Myositis-spezifische Autoantikorper (MSA) gegen t-RNA-Synthetasen, Mi-2 und SRP lassen sich nur selten bei juvenilen… Expand
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2014
2014
Identification of clinical features and autoantibodies associated with calcinosis in dermatomyositis.
IMPORTANCE Prior studies have estimated that up to 20% of adults with dermatomyositis (DM) have calcinosis, which can lead to… Expand
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Highly Cited
2013
Highly Cited
2013
Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1γ.
OBJECTIVE Since dermatomyositis (DM) is associated with an increased risk of malignancy, accurate identification of patients… Expand
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Highly Cited
2009
Highly Cited
2009
Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis
Objective The identification of novel autoantibodies in juvenile dermatomyositis (DM) may have etiologic and clinical… Expand
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2009
2009
Autoantibodies to the p140 Autoantigen NXP-2 in Adult Dermatomyositis
Purpose: Myositis-specific autoantibodies (MSAs) define dermatomyositis (DM) and polymyositis (PM) into more homogeneous clinical… Expand
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2002
2002
The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains.
Using a monoclonal antibody that recognizes a nuclear matrix protein, we selected a cDNA clone from a lambdagt11 human placenta… Expand
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