MN1 protein, human

Known as: meningioma 1 protein, human, meningioma (disrupted in balanced translocation) 1 protein, human, Probable Tumor Suppressor Protein MN1 
Probable tumor suppressor protein MN1 (1320 aa, ~136 kDa) is encoded by the human MN1 gene. This protein is involved in tumor suppression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
051019782018

Papers overview

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2011
2011
Pathways defining susceptibility of normal cells to oncogenic transformation may be valuable therapeutic targets. We… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Recently, several novel molecular prognostic markers were identified in cytogenetically normal acute myeloid leukemia (CN… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To determine the prognostic importance of the meningioma 1 (MN1) gene expression levels in the context of other… (More)
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Highly Cited
2007
Highly Cited
2007
Overexpression of wild-type MN1 is a negative prognostic factor in patients with acute myeloid leukemia (AML) with normal… (More)
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Highly Cited
2006
Highly Cited
2006
The translocation t(12;22) involves MN1 and TEL and is rarely found in acute myeloid leukemia (AML). Recently, it has been shown… (More)
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2005
2005
Fusion of the MN1 gene to TEL (ETV6) results in myeloid leukemia. The fusion protein combines the transcription activating domain… (More)
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2005
2005
The vitamin D endocrine system is essential for maintaining mineral ion homeostasis and preserving bone density. The most… (More)
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2003
2003
The t(12;22) creates an MN1–TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the… (More)
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Highly Cited
2000
Highly Cited
2000
Five strains ofa brown phototrophic sulfur bacterium (Chlorobium phaeobacteroides) were isolated from the chemocline of the Black… (More)
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2000
2000
The Tel gene (or ETV6) is the target of the translocation (12;22)(p13;q11) in myeloid leukemia. TEL is a member of the ETS family… (More)
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