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MLL/MLLT3 Fusion Gene

Known as: MLL-AF9 Fusion Gene, MLL-MLLT3 Fusion Gene, MLL/AF9 FUSION GENE 
A fusion gene that results from a chromosomal translocation t(9;11)(p22;q23) which fuses the 5' half of the MLL gene to the 3' end of the MLLT3 gene… Expand
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Chromosomal rearrangements of the MLL gene are associated with high-risk infant, pediatric, adult, and therapy-induced acute… Expand
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2013
2013
MLL rearrangements are a genetic hallmark of acute leukemia patients, which exhibit a particular poor outcome. To date, more than… Expand
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2013
2013
BackgroundThe translocation t(9;11)(p22;q23) leading to the leukemogenic fusion gene MLL-AF9 is a frequent translocation in… Expand
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2012
2012
Patients with a t(9;11) translocation (MLL-AF9) develop acute myeloid leukemia (AML), and while in mice the expression of this… Expand
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2012
2012
Although MLL-AF9 caused by the chromosomal translocation t(9;11) has a critical role in acute myeloid leukemia, the molecular… Expand
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Highly Cited
2009
Highly Cited
2009
MLL-AF4 fusion is a hallmark genetic abnormality in infant B-acute lymphoblastic leukemia (B-ALL) known to arise in utero. The… Expand
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2006
2006
Imatinib mesylate does not impair the immunogenicity of human myeloid blood dendritic cells 
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2005
2005
Chromosomal translocations involving the mixed lineage leukemia (MLL) gene are often observed in acute leukemias of both myeloid… Expand
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2005
2005
Efficient and easy detection of MLL - AF4 , MLL - AF9 and MLL - ENL fusion gene transcripts by multiplex real-time quantitative… Expand
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Highly Cited
2004
Highly Cited
2004
Identification of the targets of mixed lineage leukemia (MLL) fusion genes will assist in understanding the biology of MLL fusion… Expand
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